Evidence map›Paper›PMID 27853191›Full record

ArticleScientific reports2016

Thermal gradient induced tweezers for the manipulation of particles and cells.

Jiajie Chen, Hengji Cong, Jacky Loo, Zhiwen Kang, Minghui Tang, Haixi Zhang, Shu-Yuen Wu, Siu-Kai Kong, Ho-Pui Ho

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. Heat-Mediated Optical Manipulation.Chemical reviews · 2022
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Opto-thermophoretic fiber tweezers.Nanophotonics (Berlin, Germany) · 2019
    Article
  9. Opto-Thermophoretic Tweezers and Assembly.Journal of micro- and nano-manufacturing · 2018
    Review
  10. Review
  11. Opto-thermoelectric nanotweezers.Nature photonics · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jiajie ChenDepartment of Electronic Engineering, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, China.
Hengji CongDepartment of Electronic Engineering, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, China.
Jacky LooDepartment of Electronic Engineering, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, China.
Zhiwen KangDepartment of Electronic Engineering, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, China.
Minghui TangDepartment of Electronic Engineering, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, China.
Haixi ZhangDepartment of Electronic Engineering, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, China.
Shu-Yuen WuDepartment of Electronic Engineering, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, China.
Siu-Kai KongBiochemistry Programme, School of Life Sciences, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, China.
Ho-Pui HoDepartment of Electronic Engineering, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optical tweezers are a well-established tool for manipulating small objects. However, their integration with microfluidic devices often requires an objective lens. More importantly, trapping of non-transparent or optically sensitive targets is particularly challenging for optical tweezers. Here, for the first time, we present a photon-free trapping technique based on electro-thermally induced forces. We demonstrate that thermal-gradient-induced thermophoresis and thermal convection can lead to trapping of polystyrene spheres and live cells. While the subject of thermophoresis, particularly in the micro- and nano-scale, still remains to be fully explored, our experimental results have provided a reasonable explanation for the trapping effect. The so-called thermal tweezers, which can be readily fabricated by femtosecond laser writing, operate with low input power density and are highly versatile in terms of device configuration, thus rendering high potential for integration with microfluidic devices as well as lab-on-a-chip systems.

Indexed as

Hot TemperatureLab-On-A-Chip DevicesOptical Tweezers

Identifiers

PMID27853191
PMCPMC5113121

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.