ArticleNature communications2016
Spatially precise visual gain control mediated by a cholinergic circuit in the midbrain attention network.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Scalable nanofocusing heterojunctions for raptor-inspired on-chip vision perception.Science advances · 2026Article
- Shared subcortical arousal systems across sensory modalities during transient modulation of attention.NeuroImage · 2025Article
- Shared subcortical arousal systems across sensory modalities during transient modulation of attention.bioRxiv : the preprint server for biology · 2024Article
- Cross-modal enhancement of defensive behavior via parabigemino-collicular projections.Current biology : CB · 2024Article
- Interhemispheric competition during sleep.Nature · 2023Article
- Synaptic properties of mouse tecto-parabigeminal pathways.Frontiers in systems neuroscience · 2023Article
- Donut-like organization of inhibition underlies categorical neural responses in the midbrain.Nature communications · 2022Article
- Evolution of neural processing for visual perception in vertebrates.The Journal of comparative neurology · 2020Review
- Article
- Categorical Signaling of the Strongest Stimulus by an Inhibitory Midbrain Nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Defined Cell Types in Superior Colliculus Make Distinct Contributions to Prey Capture Behavior in the Mouse.Current biology : CB · 2019Article
- Nucleus Isthmi Is Required to Sustain Target Pursuit during Visually Guided Prey-Catching.Current biology : CB · 2019Article
- Gain control in the sensorimotor system.Current opinion in physiology · 2019Article
- Spatial Dependence of Stimulus Competition in the Avian Nucleus Isthmi Pars Magnocellularis.Brain, behavior and evolution · 2019Article
- Neural Circuits That Mediate Selective Attention: A Comparative Perspective.Trends in neurosciences · 2018Review
- Space-Specific Deficits in Visual Orientation Discrimination Caused by Lesions in the Midbrain Stimulus Selection Network.Current biology : CB · 2017Article
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2 authors.
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Abstract
A primary function of the midbrain stimulus selection network is to compute the highest-priority location for attention and gaze. Here we report the contribution of a specific cholinergic circuit to this computation. We functionally disconnected the tegmental cholinergic nucleus isthmi pars parvocellularis (Ipc) from the optic tectum (OT) in barn owls by reversibly blocking excitatory transmission in the Ipc. Focal blockade in the Ipc decreases the gain and spatial discrimination of OT units specifically for the locations represented by the visual receptive fields (VRFs) of the disconnected Ipc units, and causes OT VRFs to shift away from that location. The results demonstrate mechanisms by which this cholinergic circuit controls bottom-up stimulus competition and by which top-down signals can bias this competition, and they establish causal linkages between a particular circuit, gain control and dynamic shifts of VRFs. This circuit may perform the same function in all vertebrate species.
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