Evidence map›Paper›PMID 27852877›Full record

ArticleTransactions of the Royal Society of Tropical Medicine and Hygiene2016

Community seroprevalence survey for yaws and trachoma in the Western Division of Fiji.

Naomi Cocks, Merelesita Rainima-Qaniuci, Chelsea Yalen, Colin Macleod, Apisalome Nakolinivalu, Stephanie Migchelsen, Chrissy H Roberts, Robert Butcher, Mike Kama, David Mabey and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Transactions of the Royal Society of Tropical Medicine and Hygiene, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. The simplified trachoma grading system, amended.Bulletin of the World Health Organization · 2020
    Article
  9. Article
  10. Absence of Serological Evidence of Exposure toThe American journal of tropical medicine and hygiene · 2019
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Comparison of Platforms for Testing Antibody Responses against theThe American journal of tropical medicine and hygiene · 2017
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 4 countries.

Naomi CocksClinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
Merelesita Rainima-QaniuciWorld Health Organization, Fiji Country Office, Fiji.
Chelsea YalenClinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
Colin MacleodClinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
Apisalome NakolinivaluDepartment of Dermatology, Tamavua Twomey Hospital, Fiji.
Stephanie MigchelsenClinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
Chrissy H RobertsClinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
Robert ButcherClinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
Mike KamaFiji Centre for Communicable Disease, Ministry of Health, Suva, Fiji.
David MabeyClinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
Michael MarksClinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, Keppel Street, London WC1E 7HT, UK michael.marks@lshtm.ac.uk.
London School of Hygiene & Tropical Medicine · GBUniversity of London · GBMinistry Of Health · FJUniversity College London · GBUniversity of Fiji · FJWorld Health Organization - Pakistan · PK

Funding

Wellcome Trust 098521/B/12/ZWellcome Trust 102807Wellcome Trust 105609/Z/14/ZWorld Health Organization 001
6 · The paper itself

Abstract

backgroundBoth yaws and trachoma are endemic in several countries in the Pacific. In co-endemic countries there may be potential synergies between both control programmes.

methodsWe undertook a cluster randomised trachoma and yaws seroprevalence survey of children in the Western Division of Fiji. Children were examined for skin lesions consistent with active yaws. A dried blood spot was collected which was tested using the Treponema pallidum particle agglutination (TPPA) test and an ELISA to detect antibodies against Pgp3.

resultsA total of 607 children from 305 households across 23 villages were recruited into the survey. On skin examination, no child had clinical evidence of yaws, and the TPPA assay was negative in all children (0%, 95% CI 0.0-0.6). The seroprevalence of Pgp3 antibodies was 20.9% (95% CI 17.8-24.6%). DISCUSSION: In this study there was neither clinical nor serological evidence that transmission of yaws was ongoing. The Pgp3 seroprevalence pattern was consistent with either low level transmission of ocular Chlamydia trachomatis or exposure to C. trachomatis in the birth canal which is consistent with a survey conducted in the same region in 2013. These data suggest neither yaws nor ocular chlamydia infection are a significant public health problem in the Western Division of Fiji.

Indexed as

Health SurveysPublic HealthAdolescentAgglutination TestsChildChild, PreschoolChlamydia trachomatisCluster AnalysisDried Blood Spot TestingEnzyme-Linked Immunosorbent AssayFamily CharacteristicsFemaleFijiHumansInfantMaleFijiNeglected tropical diseasesScabiesTrachomaYaws

Identifiers

PMID27852877
PMCPMC5155547
OpenAlexW2550904415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.