ArticleJournal of immunology (Baltimore, Md. : 1950)2017
Integrin Cross-Talk Regulates the Human Neutrophil Response to Fungal β-Glucan in the Context of the Extracellular Matrix: A Prominent Role for VLA3 in the Antifungal Response.
Article in Journal of immunology (Baltimore, Md. : 1950), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 20 citations in OpenAlex.
- Mucoricin binding to β-glucan sites on germinating Mucorales spores disrupts neutrophil swarming to promote pathogenicity.bioRxiv : the preprint server for biology · 2025Article
- Cloning and Functional Analysis of Skin Host Defense Peptides from Yakushima Tago's Brown Frog (Antibiotics (Basel, Switzerland) · 2024Article
- Molecular regulation of neutrophil swarming in health and disease: Lessons from the phagocyte oxidase.iScience · 2023Review
- Targeting Neutrophil βBiomolecules · 2023Review
- A New Phenotype inmBio · 2023Article
- The formation and function of the neutrophil phagosome.Immunological reviews · 2023Review
- Akt-2 Is a Potential Therapeutic Target for Disseminated Candidiasis.Journal of immunology (Baltimore, Md. : 1950) · 2022Article
- A Fun-Guide to Innate Immune Responses to Fungal Infections.Journal of fungi (Basel, Switzerland) · 2022Review
- The emerging role of neutrophil extracellular traps in fungal infection.Frontiers in cellular and infection microbiology · 2022Review
- Neutrophil Extracellular Traps inFrontiers in immunology · 2022Review
- Substrate stiffness induces neutrophil extracellular trap (NET) formation through focal adhesion kinase activation.Biomaterials · 2021Article
- Chitotriosidase Activity Is Counterproductive in a Mouse Model of Systemic Candidiasis.Frontiers in immunology · 2021Article
- Neutrophil Swarms Are More Than the Accumulation of Cells.Microbiology insights · 2020Article
- Differential Immune Activating, Anti-Inflammatory, and Regenerative Properties of the Aqueous, Ethanol, and Solid Fractions of a Medicinal Mushroom Blend.Journal of inflammation research · 2020Article
- Noncanonical Hippo Signalling in the Regulation of Leukocyte Function.Trends in immunology · 2018Review
- Antifungal Innate Immunity: A Perspective from the Last 10 Years.Journal of innate immunity · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 4 institutions in 1 country.
Funding
Abstract
Candida albicans infection produces elongated hyphae resistant to phagocytic clearance compelling alternative neutrophil effector mechanisms to destroy these physically large microbial structures. Additionally, all tissue-based neutrophilic responses to fungal infections necessitate contact with the extracellular matrix (ECM). Neutrophils undergo a rapid, ECM-dependent mechanism of homotypic aggregation and NETosis in response to C. albicans mediated by the β
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.