Evidence map›Paper›PMID 27852740›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2017

Temporal Expression of Bim Limits the Development of Agonist-Selected Thymocytes and Skews Their TCRβ Repertoire.

Kun-Po Li, Anke Fähnrich, Eron Roy, Carla M Cuda, H Leighton Grimes, Harris R Perlman, Kathrin Kalies, David A Hildeman

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Bcl-2 Is Necessary to Counteract Bim and Promote Survival of TCRαβJournal of immunology (Baltimore, Md. : 1950) · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. T Cells and Regulated Cell Death: Kill or Be Killed.International review of cell and molecular biology · 2019
    Review
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Kun-Po LiDivision of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.ORCID 0000-0002-8872-3814
Anke FähnrichInstitute for Anatomy, University of Lübeck, 23538 Lübeck, Germany; and.
Eron RoyDivision of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.ORCID 0000-0002-7181-7929
Carla M CudaRheumatology Division, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.
H Leighton GrimesDivision of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.ORCID 0000-0001-8162-6758
Harris R PerlmanRheumatology Division, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.ORCID 0000-0003-4174-608X
Kathrin KaliesInstitute for Anatomy, University of Lübeck, 23538 Lübeck, Germany; and.ORCID 0000-0002-8929-4249
David A HildemanDivision of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229; David.Hildeman@cchmc.org.ORCID 0000-0002-0421-8483
Cincinnati Children's Hospital Medical Center · USNorthwestern University · USUniversity of Lübeck · DE

Funding

Tissue Repository CoreP30AR070549 · NIAMS · CINCINNATI CHILDRENS HOSP MED CTR · PI Leah Claire Kottyan · 2016 to 2026
$7.7M
Macrophage Modulation of Lung FibrosisR01HL134375 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PERLMAN, HARRIS R · 2017 to 2020
$2.9M
Regulation of Apoptosis in Activated Primary T CellsR01AI057753 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI HILDEMAN, DAVID A · 2005 to 2013
$2.8M
Development of a Novel RA/Atherosclerosis Mouse ModelR01AR064546 · NIAMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PERLMAN, HARRIS R · 2013 to 2017
$1.6M
NHLBI NIH HHS R01 HL134375NIAID NIH HHS R01 AI057753NIAMS NIH HHS P30 AR070549NIAMS NIH HHS R01 AR064546
6 · The paper itself

Abstract

CD8αα TCRαβ

Indexed as

Adoptive TransferAnimalsBcl-2-Like Protein 11Cell DifferentiationFlow CytometryIntestinesMiceMice, Inbred C57BLMice, KnockoutReceptors, Antigen, T-Cell, alpha-betaThymocytesT-Lymphocyte SubsetsBcl2l11 protein, mouseBcl-2-Like Protein 11Receptors, Antigen, T-Cell, alpha-beta

Identifiers

PMID27852740
PMCPMC5568849
OpenAlexW2553499461

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.