ArticleJournal of clinical microbiology2017
Rapid Identification of Measles Virus Vaccine Genotype by Real-Time PCR.
Article in Journal of clinical microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Pathogen nucleic acids data in wastewater solids from 147 treatment plants in the United States: 2024-2025.Data in brief · 2026Article
- Enhancing antitumor immunity through oncolytic viruses: advances in genetic engineering.Discover oncology · 2026Review
- Development of a dual-target measles virus PCR assay and testing trends at a national reference laboratory.Journal of clinical microbiology · 2026Article
- Diagnostic Approaches for Measles Virus: Methods, Advances, and Ongoing Challenges.Pathogens (Basel, Switzerland) · 2025Review
- Measles and rubella: From global health challenges to advancements in molecular diagnostics in the elimination era.Molecular therapy. Nucleic acids · 2025Review
- Molecular and epidemiological analysis of measles vaccine-associated rash illnesses in Shandong province, China, 2014-2021.BMC infectious diseases · 2025Article
- Updated practice for detection of viral infections in breeding macaques.Zoological research · 2025Review
- Measles vaccine virus mutation following vaccination in a healthy child resulting in a false negative vaccine specific PCR test: Ontario, Canada, 2025.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025Article
- Vaccine-Associated Measles in an Immunocompromised Host: Hospital Infection Prevention and Control and Public Health Response.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2024Article
- The Global Measles and Rubella Laboratory Network Supports High-Quality Surveillance.Vaccines · 2024Article
- Measles and Rubella Diagnostic and Classification Challenges in Near- and Post-Elimination Countries.Vaccines · 2024Review
- Implications of Measles Inclusion by Commercial Syndromic Polymerase Chain Reaction Panels - United States, May 2022-April 2023.MMWR. Morbidity and mortality weekly report · 2024Article
- Measles Resurgence in Europe: An Open Breakthrough in the Field of Vaccine-Preventable Diseases.Pathogens (Basel, Switzerland) · 2023Article
- Diagnosis of Pebrine Disease in Silkworm Using Molecular Methods.Archives of Razi Institute · 2023Article
- Oncolytic viral vectors in the era of diversified cancer therapy: from preclinical to clinical.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022Review
- Morbilliform Eruptions in the Hospitalized Child.Dermatologic clinics · 2022Review
- Formulation Development and Improved Stability of a Combination Measles and Rubella Live-Viral Vaccine Dried for Use in the NanopatchHuman vaccines & immunotherapeutics · 2021Article
- Vaccine-Associated Measles in a Hematopoietic Cell Transplant Recipient: Case Report and Comprehensive Review of the Literature.Open forum infectious diseases · 2021Article
- Co-detection of the measles vaccine and wild-type virus by real-time PCR: public health laboratory protocol.Access microbiology · 2021Article
- Measles Vaccine-Associated Rash Illness in China: an Emerging Issue in the Process of Measles Elimination.Journal of clinical microbiology · 2020Article
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During measles outbreaks, it is important to be able to rapidly distinguish between measles cases and vaccine reactions to avoid unnecessary outbreak response measures such as case isolation and contact investigations. We have developed a real-time reverse transcription-PCR (RT-PCR) method specific for genotype A measles virus (MeV) (MeVA RT-quantitative PCR [RT-qPCR]) that can identify measles vaccine strains rapidly, with high throughput, and without the need for sequencing to determine the genotype. We have evaluated the method independently in three measles reference laboratories using two platforms, the Roche LightCycler 480 system and the Applied Biosystems (ABI) 7500 real-time PCR system. In comparison to the standard real-time RT-PCR method, the MeVA RT-qPCR showed 99.5% specificity for genotype A and 94% sensitivity for both platforms. The new assay was able to detect RNA from five currently used vaccine strains, AIK-C, CAM-70, Edmonston-Zagreb, Moraten, and Shanghai-191. The MeVA RT-qPCR assay has been used successfully for measles surveillance in reference laboratories, and it could be readily deployed to national and subnational laboratories on a wide scale.
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