Evidence map›Paper›PMID 27852633›Full record

ArticleEndocrine connections2016

Predictors of malignancy in patients with pheochromocytomas/paragangliomas: Asian Indian experience.

Kranti Khadilkar, Vijaya Sarathi, Rajeev Kasaliwal, Reshma Pandit, Manjunath Goroshi, Gaurav Malhotra, Abhay Dalvi, Ganesh Bakshi, Anil Bhansali, Rajesh Rajput and 4 more

Open access · goldAbstract read
In one paragraph

Article in Endocrine connections, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Review
  4. Can Superoxide Anions Predict the Malignant Potential of Carotid body Tumor? - A Pilot Study.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. The Utility ofIndian journal of endocrinology and metabolism
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Kranti KhadilkarDepartment of EndocrinologySeth G S Medical College and KEM Hospital, Mumbai, India drkrantimd@gmail.com.
Vijaya SarathiDepartment of EndocrinologyVydehi Institute of Medical Sciences and Research Center, Bangalore, India.
Rajeev KasaliwalDepartment of EndocrinologyMahatma Gandhi Hospital and Medical College, Jaipur, India.
Reshma PanditDepartment of EndocrinologySeth G S Medical College and KEM Hospital, Mumbai, India.
Manjunath GoroshiDepartment of EndocrinologySeth G S Medical College and KEM Hospital, Mumbai, India.
Gaurav MalhotraRadiation Medicine CentreBhabha Atomic Research Centre, Mumbai, India.
Abhay DalviDepartment of General SurgerySeth G S Medical College and KEM Hospital, Mumbai, India.
Ganesh BakshiDepartment of Uro-oncologyTata Memorial Hospital, Mumbai, India.
Anil BhansaliDepartment of EndocrinologyPostgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
Rajesh RajputDepartment of EndocrinologyPt. B.D. Sharma PGIMS, Rohtak, India.
Vyankatesh ShivaneDepartment of EndocrinologySeth G S Medical College and KEM Hospital, Mumbai, India.
Anurag LilaDepartment of EndocrinologySeth G S Medical College and KEM Hospital, Mumbai, India.
Tushar BandgarDepartment of EndocrinologySeth G S Medical College and KEM Hospital, Mumbai, India.
Nalini S ShahDepartment of EndocrinologySeth G S Medical College and KEM Hospital, Mumbai, India.
King Edward Memorial Hospital and Seth G.S. Medical College · INBhabha Atomic Research Centre · INGandhi Medical College & Hospital · INInstitute of Medical Sciences · INPandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences · INPost Graduate Institute of Medical Education and Research · INTata Memorial Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsMalignant transformation of pheochromocytomas/paragangliomas (PCC/PGL) is a rare occurrence, and predictive factors for the same are not well understood. This study aims to identify the predictors of malignancy in patients with PCC/PGL. MATERIALS AND

methodsWe performed a retrospective analysis of 142 patients with either PCC or PGL registered at our institute between 2000 and 2015. Records were evaluated for clinical parameters like age, gender, familial/syndromic presentation, symptomatic presentation, biochemistry, size, number and location of tumours and presence of metastases and mode of its diagnosis.

resultsTwenty patients were found to have metastases; 13 had metastases at diagnosis and seven during follow-up. Metastases were detected by radiology (CT-neck to pelvis) in 11/20 patients (5/13 synchronous and 6/7 metachronous),

conclusionsPatients with primary tumour size >5.7 cm and lack of metanephrine secretory status should be evaluated for possible malignancy not only at diagnosis but also in the postoperative period. As compared to CT and

Indexed as

18F-flurodeoxyglucose PET/CTclinical predictorsmalignant paragangliomamalignant pheochromocytoma

Identifiers

PMID27852633
PMCPMC5314950
OpenAlexW2553590430

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.