Evidence map›Paper›PMID 27852348›Full record

Trial reportPsychological medicine2017

An adaptive randomized trial of dialectical behavior therapy and cognitive behavior therapy for binge-eating.

E Y Chen, J Cacioppo, K Fettich, R Gallop, M S McCloskey, T Olino, T A Zeffiro

Registry-linked trialOpen access · greenAbstract readAdaptive Clinical TrialRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Psychological medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00965705 (Dialectical Behavior Therapy for Early Non-Responders to CBT), which is not on this map. Cited by 22 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 5 pooled it
7.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00965705 nacompletednot on this map

Dialectical Behavior Therapy for Early Non-Responders to CBT

TypeinterventionalSponsorTemple UniversityRan2009 to 2017Enrolled109ConditionsBinge Eating DisorderArmsTherapy
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 5 syntheses or guidelines pooled it, 83 citations in OpenAlex.

  1. Emotion-Related Treatments in Patients With Binge Eating Episodes-a Systematic Review and Meta-Analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
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  5. Mechanisms and moderators in mindfulness- and acceptance-based treatments for binge eating spectrum disorders: A systematic review.European eating disorders review : the journal of the Eating Disorders Association · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

E Y ChenDepartment of Psychology,Temple University,Philadelphia, PA,USA.
J CacioppoDepartment of Psychology,The University of Chicago,Chicago, IL,USA.
K FettichDepartment of Psychology,Temple University,Philadelphia, PA,USA.
R GallopDepartment of Mathematics,West Chester University,West Chester, PA,USA.
M S McCloskeyDepartment of Psychology,Temple University,Philadelphia, PA,USA.
T OlinoDepartment of Psychology,Temple University,Philadelphia, PA,USA.
T A ZeffiroNeurometrika,Potomac, MD,USA.
Temple University · USNeuroMetrix (United States) · USUniversity of Chicago · USWest Chester University · US

Funding

Dialectical Behavior Therapy for Early Non-Responders to CBT with Binge Eating DiK23MH081030 · NIMH · UNIVERSITY OF CHICAGO · PI CHEN, EUNICE YU · 2008 to 2012
$686k
NIMH NIH HHS K23 MH081030
6 · The paper itself

Abstract

backgroundEarly weak treatment response is one of the few trans-diagnostic, treatment-agnostic predictors of poor outcome following a full treatment course. We sought to improve the outcome of clients with weak initial response to guided self-help cognitive behavior therapy (GSH).

methodOne hundred and nine women with binge-eating disorder (BED) or bulimia nervosa (BN) (DSM-IV-TR) received 4 weeks of GSH. Based on their response, they were grouped into: (1) early strong responders who continued GSH (cGSH), and early weak responders randomized to (2) dialectical behavior therapy (DBT), or (3) individual and additional group cognitive behavior therapy (CBT+).

resultsBaseline objective binge-eating-day (OBD) frequency was similar between DBT, CBT+ and cGSH. During treatment, OBD frequency reduction was significantly slower in DBT and CBT+ relative to cGSH. Relative to cGSH, OBD frequency was significantly greater at the end of DBT (d = 0.27) and CBT+ (d = 0.31) although these effects were small and within-treatment effects from baseline were large (d = 1.41, 0.95, 1.11, respectively). OBD improvements significantly diminished in all groups during 12 months follow-up but were significantly better sustained in DBT relative to cGSH (d = -0.43). At 6- and 12-month follow-up assessments, DBT, CBT and cGSH did not differ in OBD.

conclusionsEarly weak response to GSH may be overcome by additional intensive treatment. Evidence was insufficient to support superiority of either DBT or CBT+ for early weak responders relative to early strong responders in cGSH; both were helpful. Future studies using adaptive designs are needed to assess the use of early response to efficiently deliver care to large heterogeneous client groups.

Indexed as

Outcome Assessment, Health CareAdultBehavior TherapyBinge-Eating DisorderBulimia NervosaCognitive Behavioral TherapyFemaleHumansMiddle AgedYoung Adultbinge-eating disorderBulimiacognitive behavior therapydialectical behavior therapyguided self-helpstepped care

Identifiers

PMID27852348
PMCPMC7418949
OpenAlexW2555854913

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.