ArticleAttachment & human development2017
Further evidence of the limited role of candidate genes in relation to infant-mother attachment outcomes.
Article in Attachment & human development, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- The Effects of At-Birth Adoption on Atypical Behavior and Anxiety: A Nonhuman Primate Model.Journal of the American Academy of Child and Adolescent Psychiatry · 2021Trial
- Developmental cascades from early childhood attachment security to adolescent level of personality functioning among high-risk youth.Development and psychopathology · 2025Article
- Roles of the Oxytocin Receptor (OXTR) in Human Diseases.International journal of molecular sciences · 2023Review
- Neurobiology of Disorganized Attachment: A Review of Primary Studies on Human Beings.Neuroscience insights · 2023Review
- Socioemotional Mechanisms of Children's Differential Response to the Effects of Maternal Sensitivity on Child Adjustment.Parenting, science and practice · 2021Article
- An initial investigation of neonatal neuroanatomy, caregiving, and levels of disorganized behavior.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Relations between early maternal sensitivity and toddler self-regulation: Exploring variation by oxytocin and dopamine D2 receptor genes.Developmental psychobiology · 2018Article
- Testing an Attachment-Based Parenting Intervention-VIPP-FC/A in Adoptive Families with Post-institutionalized Children: Do Maternal Sensitivity and Genetic Markers Count?Frontiers in psychology · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
In this paper, we examine the associations between specific candidate genes (DRD2, DRD4, COMT, biallelic and tri-allelic 5HTTLPR, and OXTR) and infant attachment outcomes as main effects and in conjunction with maternal sensitivity. The sample included 200 infants (97 European American, 94 African-American, and 9 biracial) and their mothers. Maternal sensitivity and overtly negative maternal behavior were observed when infants were 6 months and 1 year old in distress-eliciting contexts, attachment was assessed via the Strange Situation at age 1, and DNA samples were collected when children were 2 years old. Consistent with recent research in large samples, there was little evidence that these genes are associated with attachment security, disorganization, or distress as main effects (in additive, dominant, and homozygous models) or in conjunction with maternal sensitivity or overtly negative behavior (primarily dominance models). Furthermore, there was little evidence that associations vary as a function of race.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.