Evidence map›Paper›PMID 27849262›Full record

Observational studyArquivos brasileiros de cardiologia2016

Time-To-Treatment of Acute Coronary Syndrome and Unit of First Contact in the ERICO Study.

Rafael Caire de Oliveira Dos Santos, Alessandra Carvalho Goulart, Alan Loureiro Xavier Kisukuri, Rodrigo Martins Brandão, Debora Sitnik, Henrique Lane Staniak, Marcio Sommer Bittencourt, Paulo Andrade Lotufo, Isabela Martins Bensenor, Itamar de Souza Santos

Abstract readObservational Study
In one paragraph

Observational study in Arquivos brasileiros de cardiologia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rafael Caire de Oliveira Dos SantosFaculdade de Medicina, Universidade de São Paulo, SP, Brazil.
Alessandra Carvalho GoulartHospital Universitário da Universidade de São Paulo, Faculdade de Medicina, Universidade de São Paulo, SP, Brazil.
Alan Loureiro Xavier KisukuriFaculdade de Medicina, Universidade de São Paulo, SP, Brazil.
Rodrigo Martins BrandãoHospital Universitário da Universidade de São Paulo, Faculdade de Medicina, Universidade de São Paulo, SP, Brazil.
Debora SitnikHospital Universitário da Universidade de São Paulo, Faculdade de Medicina, Universidade de São Paulo, SP, Brazil.
Henrique Lane StaniakHospital Universitário da Universidade de São Paulo, Faculdade de Medicina, Universidade de São Paulo, SP, Brazil.
Marcio Sommer BittencourtHospital Universitário da Universidade de São Paulo, Faculdade de Medicina, Universidade de São Paulo, SP, Brazil.
Paulo Andrade LotufoFaculdade de Medicina, Universidade de São Paulo, SP, Brazil.
Isabela Martins BensenorFaculdade de Medicina, Universidade de São Paulo, SP, Brazil.
Itamar de Souza SantosFaculdade de Medicina, Universidade de São Paulo, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo the best of our knowledge, there are no studies evaluating the influence of the unit of the first contact on the frequency and time of pharmacological treatment during an acute coronary syndrome (ACS) event.

objectivesThe main objective was to investigate if the unit of first contact influenced the frequency and time of aspirin treatment in the Strategy of Registry of Acute Coronary Syndrome (ERICO) study.

methodsWe analyzed the pharmacological treatment time in 830 ERICO participants - 700 individuals for whom the hospital was the unit of first contact and 130 who initially sought primary care units. We built logistic regression models to study whether the unit of first contact was associated with a treatment time of less than three hours.

resultsIndividuals who went to primary care units received the first aspirin dose in those units in 75.6% of the cases. The remaining 24.4% received aspirin at the hospital. Despite this finding, individuals from primary care still had aspirin administered within three hours more frequently than those who went to the hospital (76.8% vs 52.6%; p<0.001 and 100% vs. 70.7%; p=0.001 for non ST-elevation ACS and ST-elevation myocardial infarction, respectively). In adjusted models, individuals coming from primary care were more likely to receive aspirin more quickly (odds ratio: 3.66; 95% confidence interval: 2.06-6.51).

conclusionsIn our setting, individuals from primary care were more likely to receive aspirin earlier. Enhancing the ability of primary care units to provide early treatment and safe transportation may be beneficial in similar settings.

Indexed as

Acute Coronary SyndromeAgedAnticoagulantsAspirinBrazilClopidogrelEducational StatusFemaleFibrinolytic AgentsHeparinHumansMaleMiddle AgedPlatelet Aggregation InhibitorsPrimary Health CareProspective StudiesAnticoagulantsAspirinClopidogrelFibrinolytic AgentsHeparinPlatelet Aggregation InhibitorsTiclopidine

Identifiers

PMID27849262
PMCPMC5102478

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.