Evidence map›Paper›PMID 27849177›Full record

ArticleInfection and immunity2017

Interplay of Toll-Like Receptor 9, Myeloid Cells, and Deubiquitinase A20 in Periodontal Inflammation.

Katie E Crump, Jennifer C Oakley, Xia Xia-Juan, Theandra C Madu, Swathi Devaki, Erin C Mooney, Sinem E Sahingur

Abstract read
In one paragraph

Article in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
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  14. International journal of molecular sciences · 2022
    Article
  15. Article
  16. Review
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Katie E CrumpDepartment of Periodontics, Virginia Commonwealth University, School of Dentistry, Richmond, Virginia, USA.
Jennifer C OakleyDepartment of Periodontics, Virginia Commonwealth University, School of Dentistry, Richmond, Virginia, USA.
Xia Xia-JuanDepartment of Periodontics, Virginia Commonwealth University, School of Dentistry, Richmond, Virginia, USA.
Theandra C MaduDepartment of Periodontics, Virginia Commonwealth University, School of Dentistry, Richmond, Virginia, USA.
Swathi DevakiDepartment of Periodontics, Virginia Commonwealth University, School of Dentistry, Richmond, Virginia, USA.
Erin C MooneyDepartment of Periodontics, Virginia Commonwealth University, School of Dentistry, Richmond, Virginia, USA.
Sinem E SahingurDepartment of Periodontics, Virginia Commonwealth University, School of Dentistry, Richmond, Virginia, USA ssahingur@vcu.edu.

Funding

Virginia Commonwealth University IRADCAK12GM093857 · NIGMS · VIRGINIA COMMONWEALTH UNIVERSITY · PI DANIEL C BULLARD, John J Ryan · 2010 to 2026
$7.0M
Microbial Nucleic Acid Sensing in PeriodontitisR01DE025037 · NIDCR · VIRGINIA COMMONWEALTH UNIVERSITY · PI SAHINGUR, SINEM ESRA · 2015 to 2019
$1.9M
Center for Clinical and Translational ResearchKL2TR000057 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI MOELLER, FREDERICK GERARD · 2012 to 2014
$1.4M
Inflammatory responses initiated by periodontal bacterial DNAR03DE022836 · NIDCR · VIRGINIA COMMONWEALTH UNIVERSITY · PI SAHINGUR, SINEM ESRA · 2013 to 2014
$229k
NCATS NIH HHS KL2 TR000057NIDCR NIH HHS R01 DE025037NIDCR NIH HHS R03 DE022836NIGMS NIH HHS K12 GM093857
6 · The paper itself

Abstract

Toll-like receptor 9 (TLR9)-deficient (TLR9

Indexed as

AdultAgedAged, 80 and overAlveolar Bone LossAnimalsBacteroidaceae InfectionsChronic PeriodontitisDeubiquitinating EnzymesFemaleGingivaHumansInflammationMacrophagesMaleMiceMice, Inbred BALB CDeubiquitinating EnzymesNF-kappa BTLR9 protein, humanTNFAIP3 protein, humanToll-Like Receptor 9Tumor Necrosis Factor alpha-Induced Protein 3A20cytokineinflammationperiodontal diseaseTNFAIP3Toll-like receptor

Identifiers

PMID27849177
PMCPMC5203663

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.