Observational studyJournal of the American Heart Association2016
Neurological Injury in Intermediate-Risk Transcatheter Aortic Valve Implantation.
Observational study in Journal of the American Heart Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 4 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Incidence and Risk Factors for Silent Brain Infarction After On-Pump Cardiac Surgery: A Meta-analysis and Meta-regression of 29 Prospective Cohort Studies.Neurocritical care · 2021Pooled it
- Meta-Analysis of Prevalence and Risk Factors for Cognitive Decline and Improvement After Transcatheter Aortic Valve Implantation.The American journal of cardiology · 2020Pooled it
- Silent Brain Infarcts Following Cardiac Procedures: A Systematic Review and Meta-Analysis.Journal of the American Heart Association · 2019Pooled it
- Meta-analysis of Prevalence and Risk Factors for Delirium After Transcatheter Aortic Valve Implantation.The American journal of cardiology · 2018Pooled it
- Evaluation of neurocognitive function changes based on the full neuropsychological test battery after transcatheter aortic valve replacement under monitored anaesthesia care.BMC geriatrics · 2025Observational
- Clinical and subclinical acute brain injury caused by invasive cardiovascular procedures.Nature reviews. Cardiology · 2025Review
- Cerebral Protection in Trans-Catheter Aortic Valve Replacement: Review and Contemporary Assessment of Randomized Trial Data.The Neurohospitalist · 2024Review
- Neurocognitive function in procedures correcting severe aortic valve stenosis: patterns and determinants.Frontiers in cardiovascular medicine · 2024Article
- [Delayed cognitive impairment in patients with aortic stenosis treated with surgical valve replacement and transcatheter aortic valve implantation: a comparative study].Revista de neurologia · 2023Observational
- Postoperative delirium in 47 379 individuals undergoing transcatheter aortic valve replacement: a systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2023Review
- Article
- Article
- Prevalence and severity of cognitive dysfunction in patients referred for transcatheter aortic valve implantation (TAVI): clinical and cognitive impact at 1 year.Aging clinical and experimental research · 2022Article
- Effect of Balloon Guide Catheter Utilization on the Incidence of Sub-angiographic Peripheral Emboli on High-Resolution DWI After Thrombectomy: A Prospective Observational Study.Frontiers in neurology · 2020Article
- Differential immunological profiles herald magnetic resonance imaging-defined perioperative cerebral infarction.Therapeutic advances in neurological disorders · 2018Article
- Early cerebrovascular events after transcatheter aortic valve replacement: patient- and procedure-specific predictors.Journal of thoracic disease · 2017Article
- Cerebral Embolic Risk in Coronary and Structural Heart Interventions: Clinical Evidence.Journal of the Society for Cardiovascular Angiography & InterventionsReview
Corrections and comments
- Erratum issued
Authors and funding
12 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe application of transcatheter aortic valve implantation (TAVI) to intermediate-risk patients is a controversial issue. Of concern, neurological injury in this group remains poorly defined. Among high-risk and inoperable patients, subclinical injury is reported on average in 75% undergoing the procedure. Although this attendant risk may be acceptable in higher-risk patients, it may not be so in those of lower risk. METHODS AND
resultsForty patients undergoing TAVI with the Edwards SAPIEN-XT
conclusionsObjectively measured subclinical neurological injuries remain a concern in intermediate-risk patients undergoing TAVI and are likely to manifest with early neurocognitive changes. CLINICAL
trial registrationURL: http://www.anzctr.org.au. Australian & New Zealand Clinical Trials Registry: ACTRN12613000083796.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.