ArticleScientific reports2016
Evolutionarily conserved odorant receptor function questions ecological context of octenol role in mosquitoes.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 46 citations in OpenAlex.
- Sensory coding of borneol repellency in culicine mosquitoes via the Or49 pathway.Nature communications · 2026Article
- The olfactory neurobiology and chemical ecology of mosquito attraction to plant nutrient sources.Proceedings. Biological sciences · 2025Review
- The chemosensory world of mosquitoes: olfactory receptors and their role in blocking mosquito-borne disease transmission.Parasites & vectors · 2025Review
- A conserved odorant receptor underpins borneol-mediated repellency in culicine mosquitoes.bioRxiv : the preprint server for biology · 2024Article
- Odor-evoked transcriptomics of Aedes aegypti mosquitoes.PloS one · 2023Article
- The ovipositor cue indole inhibits animal host attraction in Aedes aegypti (Diptera: Culicidae) mosquitoes.Parasites & vectors · 2022Article
- Odorant receptor orthologues in conifer-feeding beetles display conserved responses to ecologically relevant odours.Molecular ecology · 2022Article
- Article
- Review
- Functional conservation of Anopheline linalool receptors through 100 million years of evolution.Chemical senses · 2022Article
- Characterization ofInsects · 2021Article
- The Expression of Chemosensory Genes in Male Maxillary Palps of Anopheles coluzzii (Diptera: Culicidae) and An. quadriannulatus.Journal of medical entomology · 2021Article
- Olfactory systems across mosquito species.Cell and tissue research · 2021Review
- Review
- Volatile Cues Influence Host-Choice in Arthropod Pests.Animals : an open access journal from MDPI · 2020Review
- Species and sex-specific chemosensory gene expression in Anopheles coluzzii and An. quadriannulatus antennae.Parasites & vectors · 2020Article
- An odorant receptor from Anopheles gambiae that demonstrates enantioselectivity to the plant volatile, linalool.PloS one · 2019Article
- Membrane Proteins Mediating Reception and Transduction in Chemosensory Neurons in Mosquitoes.Frontiers in physiology · 2018Review
- Socio-Ecological Mechanisms Supporting High Densities of Aedes albopictus (Diptera: Culicidae) in Baltimore, MD.Journal of medical entomology · 2017Article
- Volatile allosteric antagonists of mosquito odorant receptors inhibit human-host attraction.The Journal of biological chemistryArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Olfaction is a key insect adaptation to a wide range of habitats. In the last thirty years, the detection of octenol by blood-feeding insects has been primarily understood in the context of animal host-seeking. The recent discovery of a conserved octenol receptor gene in the strictly nectar-feeding elephant mosquito Toxorhynchites amboinensis (TaOr8) suggests a different biological role. Here, we show that TaOR8 is a functional ortholog of its counterparts in blood-feeding mosquitoes displaying selectivity towards the (R)-enantiomer of octenol and susceptibility to the insect repellent DEET. These findings suggest that while the function of OR8 has been maintained throughout mosquito evolution, the context in which this receptor is operating has diverged in blood and nectar-feeding mosquitoes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.