Evidence map›Paper›PMID 27848207›Full record

ArticleMolecular neurobiology2017

Primary Role for Kinin B

Natália Fontana Nicoletti, Jacques Sénécal, Vinicius Duval da Silva, Marcelo R Roxo, Nelson Pires Ferreira, Rafael Leite T de Morais, João Bosco Pesquero, Maria Martha Campos, Réjean Couture, Fernanda Bueno Morrone

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Review
  3. Kinin BPharmaceuticals (Basel, Switzerland) · 2025
    Article
  4. Review
  5. Glioma and Peptidergic Systems: Oncogenic and Anticancer Peptides.International journal of molecular sciences · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Kinins in Glioblastoma Microenvironment.Cancer microenvironment : official journal of the International Cancer Microenvironment Society · 2019
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Natália Fontana NicolettiPrograma de Pós-Graduação em Biologia Celular e Molecular, PUCRS, Avenida Ipiranga 6681, Porto Alegre, RS, 90619-900, Brazil.
Jacques SénécalDepartment of Molecular and Integrative Physiology, Faculty of Medicine, Université de Montréal, C.P. 6128, Succursale Centre-ville, Montreal H3C 3J7, QC, Canada.
Vinicius Duval da SilvaLaboratório de Patologia, PUCRS, Hospital São Lucas, Avenida Ipiranga, 6681, Porto Alegre, RS, 90619-900, Brazil.
Marcelo R RoxoServiço de Neurocirurgia, Hospital São José, Irmandade da Santa Casa de Misericórdia de Porto Alegre, Rua Professor Annes Dias 295, Porto Alegre, RS, 90020-090, Brazil.
Nelson Pires FerreiraServiço de Neurocirurgia, Hospital São José, Irmandade da Santa Casa de Misericórdia de Porto Alegre, Rua Professor Annes Dias 295, Porto Alegre, RS, 90020-090, Brazil.
Rafael Leite T de MoraisDepartamento de Biofísica, Universidade Federal de São Paulo, Avenida Doutor Arnaldo 455, Sao Paulo, SP, 01246-903, Brazil.
João Bosco PesqueroDepartamento de Biofísica, Universidade Federal de São Paulo, Avenida Doutor Arnaldo 455, Sao Paulo, SP, 01246-903, Brazil.
Maria Martha CamposPrograma de Pós-Graduação em Biologia Celular e Molecular, PUCRS, Avenida Ipiranga 6681, Porto Alegre, RS, 90619-900, Brazil.
Réjean CoutureDepartment of Molecular and Integrative Physiology, Faculty of Medicine, Université de Montréal, C.P. 6128, Succursale Centre-ville, Montreal H3C 3J7, QC, Canada. rejean.couture@umontreal.ca.
Fernanda Bueno MorronePrograma de Pós-Graduação em Biologia Celular e Molecular, PUCRS, Avenida Ipiranga 6681, Porto Alegre, RS, 90619-900, Brazil. fernanda.morrone@pucrs.br.
Pontifícia Universidade Católica do Rio Grande do Sul · BRSanta Casa Hospital · BRUniversidade Federal de São Paulo · BRUniversité de Montréal · CAHospital São Lucas da PUCRS · BR

Funding

Canadian Institutes of Health Research MOP-119329Financiadora de Estudos e Projetos 01.11.0014-00
6 · The paper itself

Abstract

This study investigated the role of kinins and their receptors in malignant brain tumors. As a first approach, GL-261 glioma cells were injected (2 × 10

Indexed as

AnimalsAstrocytesBradykininBrain NeoplasmsCell ProliferationDioxolesGliomaMiceMice, KnockoutReceptor, Bradykinin B1Receptor, Bradykinin B2SulfonamidesUp-Regulation2-((3-(1,3-benzodioxol-5-yl)-3-(((6-methoxy-2-naphthyl)sulfonyl)amino)propanoyl)amino)-3-(4-((2,6-dimethylpiperidinyl)methyl)phenyl)-N-isopropyl-N-methylpropanamideBradykininDioxolesicatibantReceptor, Bradykinin B1Receptor, Bradykinin B2SulfonamidesB1R and B2RGlioblastomaKinins

Identifiers

PMID27848207
OpenAlexW2556124714

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.