Evidence map›Paper›PMID 27848185›Full record

ArticleInternational journal of hematology2017

Pediatric intestinal Behçet disease complicated by myeloid malignancies.

Kiichiro Kanamitsu, Akira Shimada, Ritsuo Nishiuchi, Tomonari Shigemura, Yozo Nakazawa, Kenichi Koike, Yuichi Kodama, Yuichi Shinkoda, Yoshifumi Kawano, Kozo Yasui and 4 more

Abstract read
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In one paragraph

Article in International journal of hematology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Kiichiro KanamitsuDepartment of Pediatric Hematology/Oncology, Okayama University Hospital, Okayama, 2-5-1, Shikatacho, Kitaku, Okayama, 700-8558, Japan.
Akira ShimadaDepartment of Pediatric Hematology/Oncology, Okayama University Hospital, Okayama, 2-5-1, Shikatacho, Kitaku, Okayama, 700-8558, Japan. pajj236e@okayama-u.ac.jp.ORCID http://orcid.org/0000-0001-5207-3779
Ritsuo NishiuchiDepartment of Pediatrics, Kochi Health Sciences Center, Kochi, Japan.
Tomonari ShigemuraDepartment of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan.
Yozo NakazawaDepartment of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan.
Kenichi KoikeDepartment of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan.
Yuichi KodamaDepartment of Pediatrics, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Yuichi ShinkodaDepartment of Pediatrics, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Yoshifumi KawanoDepartment of Pediatrics, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Kozo YasuiDepartment of Pediatrics, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.
Koji SasakiDepartment of Pediatrics, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Ryosuke KajiwaraDepartment of Pediatrics, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Hirokazu TsukaharaDepartment of Pediatric Hematology/Oncology, Okayama University Hospital, Okayama, 2-5-1, Shikatacho, Kitaku, Okayama, 700-8558, Japan.
Atsushi ManabeDepartment of Pediatrics, St. Luke's International Hospital, Tokyo, Japan.
Kagoshima University · JPOkayama University Hospital · JPShinshu University · JPYokohama City University · JPHiroshima City Asa Citizens Hospital · JPSt. Luke's International Hospital · JPUniversity of Kochi · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Behçet disease (BD) is rarely seen in children. Its clinical manifestations are believed to differ between pediatric and adult patients. The characteristics of BD complicated by myelodysplastic syndrome (MDS) are well established for adult patients; however, because only a few cases of pediatric-onset BD complicated by MDS have been reported, its clinical characteristics remain unknown. We here retrospectively review pediatric-onset BD complicated by myeloid malignancies in Japan, having identified five such patients. All patients were female and had gastrointestinal involvements, but lacked both major features of BD, i.e., uveitis and association with HLA-B51. All patients had advanced MDS or acute myeloid leukemia and received chemotherapy followed by hematopoietic stem cell transplantation. These five cases suggest that intestinal BD and myeloid malignancies have one or more pathophysiological mechanisms in common.

Indexed as

Antineoplastic AgentsBehcet SyndromeChildChild, PreschoolFemaleHematopoietic Stem Cell TransplantationHumansIntestinal DiseasesJapanLeukemia, Myeloid, AcuteMyelodysplastic SyndromesRetrospective StudiesAntineoplastic AgentsGastrointestinal involvementsMyeloid malignanciesPediatric-onset Behçet disease

Identifiers

PMID27848185
OpenAlexW2549986306

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.