Evidence map›Paper›PMID 27848107›Full record

ArticleMedicine, health care, and philosophy2017

Defining disease in the context of overdiagnosis.

Mary Jean Walker, Wendy Rogers

Abstract read
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Article in Medicine, health care, and philosophy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Conceptual scaffolding for the philosophy of medicine.Medicine, health care, and philosophy · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. How to Draw the Line Between Health and Disease? Start with Suffering.Health care analysis : HCA : journal of health philosophy and policy · 2021
    Article
  9. Overdiagnosis: one concept, three perspectives, and a model.European journal of epidemiology · 2021
    Article
  10. Reducing overdiagnosis in primary care is needed.The European journal of general practice · 2017
    Article
  11. Article
  12. Article
  13. Overdiagnostic uncertainty.European journal of epidemiology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mary Jean WalkerPhilosophy Department, Macquarie University, Sydney, 2109, Australia. mary.walker@mq.edu.au.
Wendy RogersPhilosophy Department and the Department of Clinical Medicine, Macquarie University, Sydney, 2109, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, concerns have been raised about the phenomenon of 'overdiagnosis', the diagnosis of a condition that is not causing harm, and will not come to cause harm. Along with practical, ethical, and scientific questions, overdiagnosis raises questions about our concept of disease. In this paper, we analyse overdiagnosis as an epistemic problem and show how it challenges many existing accounts of disease. In particular, it raises questions about conceptual links drawn between disease and dysfunction, harm, and risk. We argue that 'disease' should be considered a vague concept with a non-classical structure. On this view, overdiagnosed cases are 'borderline' cases of disease, falling in the zone between cases that are clearly disease, and cases that are clearly not disease. We then develop a précising definition of disease designed to provide practical help in preventing and limiting overdiagnosis. We argue that for this purpose, we can define disease as dysfunction that has a significant risk of causing severe harm to the patient.

Indexed as

Medical OveruseDiagnosis, DifferentialHumansRiskDisease definitionDysfunctionOverdiagnosisPrécising definitionSpectral disease

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.