Observational studyInternational urology and nephrology2017
Concordance of renal stone culture: PMUC, RPUC, RSC and post-PCNL sepsis-a non-randomized prospective observation cohort study.
Observational study in International urology and nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05202158 (A Novel Method for Stone Area Sterilization During Retrograde Intrarenal Surgery), which is not on this map. Cited by 27 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Novel Method for Stone Area Sterilization During Retrograde Intrarenal Surgery (RIRS)
Who cites it
27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Stone culture, bladder or pelvic urine culture: the most helpful tool for an endourologist - a review of literature from EAU section of endourology.World journal of urology · 2025Pooled it
- Clinical significance of stone culture during endourological procedures in predicting post-operative urinary sepsis: should it be a standard of care-evidence from a systematic review and meta-analysis from EAU section of Urolithiasis (EULIS).World journal of urology · 2024Pooled it
- International Alliance of Urolithiasis (IAU) guideline on staghorn calculi management.World journal of urology · 2024Guideline
- The influencing factors of infectious complications after percutaneous nephrolithotomy: a systematic review and meta-analysis.Urolithiasis · 2022Pooled it
- Antibacterial effect of fosfomycin tromethamine on the bacteria inside urinary infection stones.International urology and nephrology · 2020Trial
- Urinary Tract Infectious Complications After Retrograde Intrarenal Surgery: The RIRS-STAMP Risk Score from a Two-Center Cohort.Pathogens (Basel, Switzerland) · 2026Article
- The development and internal validation of a rating scale system in predicting renal stone bacteria culture positivity before PCNL: a cross-sectional study.Urolithiasis · 2026Article
- Safety and efficacy of flexible and navigable suction combined with retrograde flexible ureteroscopy in the management of infectious stones.BMC infectious diseases · 2025Article
- International Alliance of Urolithiasis (IAU) consensus on miniaturized percutaneous nephrolithotomy.Military Medical Research · 2024Article
- Article
- A new protocol for renal collecting system sterilization with antibiotic irrigation during lithotripsy in retrograde intrarenal surgery: a prospective, comparative study.World journal of urology · 2024Article
- Characteristics of Bacteria in Urine and Stones from Patients Treated with Percutaneous Nephrolithotomy and Association with Postoperative Infection.Infection and drug resistance · 2024Article
- Metabolic stone workup abnormalities are not as important as stone culture in patients with recurrent stones undergoing percutaneous nephrolithotomy.Urolithiasis · 2023Article
- Can we identify the risk factors for SIRS/sepsis after percutaneous nephrolithotomy? A meta‑analysis and literature review.Experimental and therapeutic medicine · 2023Article
- Investigation of Virulence Genes of the Predominant Bacteria Associated with Renal Stones and their Correlation with Postoperative Septic Complications.Infection and drug resistance · 2022Article
- Preoperative antibiotic therapy exceeding 7 days can minimize infectious complications after percutaneous nephrolithotomy in patients with positive urine culture.World journal of urology · 2022Article
- Miniaturized percutaneous Nephrolithotomy without antibiotic prophylaxis: a single institution experience.International urology and nephrology · 2021Article
- Renal pelvis urine Gram stain as a traditional, but new marker in predicting postoperative fever and stone culture positivity in percutaneous nephrolithotomy: an observational, prospective, non-randomized cohort study.World journal of urology · 2021Observational
- A quick stone component analysis matters in postoperative fever: a propensity score matching study of 1493 retrograde intrarenal surgery.World journal of urology · 2021Article
- Indwelling catheterization, renal stones, and hydronephrosis are risk factors for symptomatic Staphylococcus aureus-related urinary tract infection.World journal of urology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionBetween 5 and 10% of patients undergoing percutaneous nephrolithotomy (PCNL) develop postoperative sepsis 1, 2. Strategies to prevent infectious complications are based on information provided by preoperative midstream urine cultures (PMUC). The aim of this study is to evaluate the concordance of the microbiologic findings of PMUC, cultures of the renal stone (RSC) and urine obtained directly from the renal pelvis (RPUC) in patients undergoing PCNL. MATERIALS AND
methodsThis is a multicenter prospective study. The study included all patients who underwent PCNL from May 2013 to July 2015 in three academic hospitals. All patients underwent a PMUC. Samples for RPUC were obtained by renal puncture for PCNL. Stone fragments extracted during the procedure were sent for culture (RSC). Clinical variables, stone configuration, burden and microbiology reports of cultures were recorded. We analyzed concordance between cultures and association with infectious complications.
resultsOne hundred and twenty-two patients underwent PCNL. Twenty-four percent had positive culture, 3.2% (4/122) PMUC, 14.7% (18/122) RPUC and 13.9% (17/122) RSC. Positive PMUC demonstrated multidrug-susceptible Escherichia coli and Staphylococcus aureus, while RPUC showed multidrug-resistant pathogens and/or fungus. Seven patients (5.7%) developed postoperative infectious complications prior to discharge. There was a weak correlation between PMUC and intraoperative urine cultures (RPUC and RSC). Concordance rate between RPUC and RSC was 83.3%. The most common isolated pathogens were multidrug-resistant bacteria or fungus.
conclusionsPMUC did not reflect the microbiological environment found in stones and urine directly obtained from the renal pelvis. Patients with postoperative infectious complications had negative PMUC with positive RPUC or RSC. RPUC and RSC can help guide prompt and appropriate antibiotic treatment for patients who develop postoperative infectious complications after PCNL.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.