Evidence map›Paper›PMID 27848022›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2017

Is there a change in the quality of life comparing the micro-invasive glaucoma surgery (MIGS) and the filtration technique trabeculectomy in glaucoma patients?

Milena Pahlitzsch, Matthias K J Klamann, Marie-Luise Pahlitzsch, Johannes Gonnermann, Necip Torun, Eckart Bertelmann

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Managing the ocular surface after glaucoma filtration surgery: an orphan topic.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. TGF-Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  11. iStent for Adults With Glaucoma: A Health Technology Assessment.Ontario health technology assessment series · 2021
    Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Xen45 Gel Stent implant: patient reported outcomes.International journal of ophthalmology · 2019
    Article
  17. Evolution of Glaucoma Surgery in the Last 25 Years.Rambam Maimonides medical journal · 2018
    Review
  18. Article
  19. XENInternational journal of ophthalmology · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Milena PahlitzschCampus Virchow Clinic, Department of Ophthalmology, Charité University Medicine, Augustenburger Platz 1, 13353, Berlin, Germany. milena.pahlitzsch@charite.de.
Matthias K J KlamannCampus Virchow Clinic, Department of Ophthalmology, Charité University Medicine, Augustenburger Platz 1, 13353, Berlin, Germany.
Marie-Luise PahlitzschEye Clinic Wittenbergplatz, Kleiststr. 23-26, 10787, Berlin, Germany.
Johannes GonnermannCampus Virchow Clinic, Department of Ophthalmology, Charité University Medicine, Augustenburger Platz 1, 13353, Berlin, Germany.
Necip TorunCampus Virchow Clinic, Department of Ophthalmology, Charité University Medicine, Augustenburger Platz 1, 13353, Berlin, Germany.
Eckart BertelmannCampus Virchow Clinic, Department of Ophthalmology, Charité University Medicine, Augustenburger Platz 1, 13353, Berlin, Germany.
Charité - Universitätsmedizin Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study was conducted to assess the impact on the Quality of Life (QOL) of micro-invasive glaucoma surgery (MIGS: iStent, Trabectome) and a penetrating technique such as Trabeculectomy (TE).

methodsThis study evaluated 88 eyes of 88 open angle glaucoma patients undergoing glaucoma surgery: 43 (mean age 72.8 ± 8.8y, female 59.5 %, male 40.5 %) Trabectome (NeoMedix, Inc., Tustin, CA, USA), 20 (mean age 68.6 ± 16.4y, female 60 %, male 40 %) iStent (Glaucos Corporation, Laguna Hills, CA, USA), and 25 TE patients (mean age 74.2 ± 9.1y female 58.3 %, male 41.7 %). The National Eye Institute-Visual Functioning Questionnaire (VFQ-25) survey was used to assess the QOL at 6 months post surgery. The following 12 QOL parameters were evaluated: general health, ocular pain, general vision, near and distance activities, mental health, social functioning, role difficulties, dependency, driving, color vision, and peripheral vision. Intraocular pressure (IOP), number of topical medications, and visual acuity (VA) were examined preoperatively, 1 day, 6 weeks, 3 months, and 6 months post surgery. Statistical data were calculated using SPSS (v20.0, SPSS, Inc.).

resultsThere was no significant difference between TE and MIGS in the quality of life 6 months postoperatively. IOP was significantly lower in TE compared to MIGS at 6 weeks and 3 months postoperatively (p = 0.046 and p = 0.046). Number of medications was significantly decreased in TE compared to MIGS (p < 0.001). A significant difference in VA between TE and MIGS could be assessed at day 1 post-op (p = 0.011).

conclusionIn this study cohort, the QOL can be maintained by all three surgical techniques. Patients, however, need lower numbers of topical medication in TE, which would impact QOL even though it is not included in the NEI-VFQ-25. The decision of the most appropriate surgical technique should be made by including single QOL categories, IOP and glaucoma medication outcome.

Indexed as

Quality of LifeVisual AcuityAgedFemaleFiltering SurgeryFollow-Up StudiesGlaucomaHumansIntraocular PressureMaleMinimally Invasive Surgical ProceduresProspective StudiesSurveys and QuestionnairesTime FactorsTonometry, OcularTrabeculectomyiStentMicro-invasive glaucoma surgeryQuality of lifeTrabeculectomy

Identifiers

PMID27848022
OpenAlexW2551928022

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.