ArticleJournal of investigative medicine high impact case reports
Relapsed Acinic Cell Carcinoma of the Parotid Gland With Diffuse Distant Metastasis: Case Report With Literature Review.
Article in Journal of investigative medicine high impact case reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 18 citations in OpenAlex.
- A Case of Acinic Cell Carcinoma Metastasizing to the Heart.Head and neck pathology · 2025Article
- Chaotic transformation of parotid acinic cell carcinoma to metastatic dedifferentiated high-grade pathology - A rare case with clinical and emotional challenge.International journal of surgery case reports · 2023Article
- Recurrent acinic cell carcinoma of the parotid gland with lateral skull base invasion: Case report and discussion of the literature.Clinical case reports · 2023Article
- Blindness Following Endoscopic Excision of Acinic Cell Carcinoma of Sphenoid Sinus: A Case Report.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
- A Rare Case of Brain Metastasis from Dedifferentiated Acinic Cell Carcinoma of the Parotid Gland and Review of the Literature.Iranian journal of pathology · 2022Article
- Acinic cell carcinoma of the parotid gland: from pathogenesis to management: a literature review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2020Review
- Parotid adenocarcinoma metastasis to the breast: a case report.Journal of surgical case reports · 2020Article
- Predictors of distant metastasis in acinic cell carcinoma of the parotid gland.World journal of clinical oncology · 2020Article
- Which Surgical Method is Superior for the Treatment of Parotid Tumor? Is it Classical? Is it New?The Eurasian journal of medicine · 2019Article
- Ectopic Cushing's Syndrome Unveiling a Metastatic Parotid Carcinoma.Case reports in endocrinology · 2019Article
- Close Margins and Adjuvant Radiotherapy in Acinic Cell Carcinoma of the Parotid Gland.JAMA otolaryngology-- head & neck surgery · 2018Article
- Ectopic Cushing's Syndrome Secondary to Acinic Cell Carcinoma of the Parotid Gland: A Case Report.Case reports in oncologyArticle
- Ectopic ACTH Secretion Secondary to Metastatic Acinic Cell Carcinoma of the Parotid Gland: A Case Report and Review of Current Evidence for Systemic Therapy.Journal of investigative medicine high impact case reportsReview
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acinic cell carcinoma (ACC) is an uncommon salivary gland neoplasm that generally displays an indolent growth pattern. Most cases arise in the major glands, particularly the parotid. However, it can arise from minor salivary glands in the oral cavity and aero-digestive tract. Although ACC is generally a low-grade malignant tumor, poorly differentiated and high-grade transformed variants exhibit a propensity for late recurrence and metastasis. There are no adequate clinical trials that define the optimal approach to patients with metastatic salivary gland tumors due to its rarity. Systemic therapy is reserved for cases where local therapy, such as radiation or metastasectomy, is not appropriate. Nevertheless, there is insufficient data in the literature regarding the chemotherapy of choice for metastatic ACC. In this article, we report a case of metastatic ACC of the right parotid gland that progressed on carboplatin and paclitaxel after partial response followed by doxorubicin and is currently on checkpoint inhibitor treatment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.