ArticleInternational journal of retina and vitreous2016
Intralesional antibiotic injection using 41G needle for the management of subretinal abscess in endogenous endophthalmitis.
Article in International journal of retina and vitreous, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- Article
- Surgical approach to endophthalmitis: an overview.Eye (London, England) · 2024Review
- Subretinal recombinant human tissue plasminogen activator injection using a 41G needle for the management of submacular hemorrhages: a 3-case report.International journal of ophthalmology · 2023Article
- Subretinal abscess: causative pathogens, clinical features and management.Journal of ophthalmic inflammation and infection · 2022Review
- HypervirulentLife (Basel, Switzerland) · 2021Review
- Metastatic subretinal abscess in a patient with perinephric abscess.Indian journal of ophthalmology · 2020Article
- Successful treatment of endogenous endophthalmitis with extensive subretinal abscess: a case report.BMC ophthalmology · 2018Article
- Evaluation of rhegmatogenous retinal detachments using Optos ultrawide field fundus fluorescein angiography and comparison with ETDRS 7 field overlay.Journal of current ophthalmology · 2018Article
- Surgical cystotomy for refractory diabetic cystoid macular edema.Clinical ophthalmology (Auckland, N.Z.) · 2018Article
- Subretinal Hypopyon in Presumed Tubercular Uveitis: A Report of Two Cases.Middle East African journal of ophthalmologyArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPresence of subretinal abscess in endogenous endophthalmitis indicates a more severe form of infection. Available reports indicate variable response to standard treatment with systemic, intravitreal pharmacotherapy and vitreous surgery. There are no reports citing the possible role of intralesional antibiotic therapy in managing subretinal abscess. CASE PRESENTATION: A 30 year old lady presented with features of endogenous endophthalmitis and subretinal abscess. Presenting vision was finger counting close to face. Despite prompt initiation of systemic antibiotics and intravitreal injection, no response was noted. 25G pars plana vitrectomy was performed along with injection of vancomycin directly into the subretinal abscess, using a 41G needle. Postoperative course was uneventful and the abscess showed signs of rapid resolution. Visual acuity improved to 6/24.
conclusionIntralesional pharmacotherapy may be safe and effective in the treatment of subretinal abscess associated with endogenous endophthalmitis.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.