ReviewWorld journal of cardiology2016
Physical activity in primary and secondary prevention of cardiovascular disease: Overview updated.
Review in World journal of cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
73 citing papers in PubMed, 6 syntheses or guidelines pooled it, 192 citations in OpenAlex.
- Effectiveness of maintenance interventions promoting physical activity following exercise therapy for chronic conditions: an umbrella review.British journal of sports medicine · 2026Pooled it
- Aerobic physical activity, cardiorespiratory fitness, and non-communicable diseases risk in older adults: a systematic review.BMC geriatrics · 2026Pooled it
- Leisure-time and occupational physical activity and risk of cardiovascular disease incidence: a systematic-review and dose-response meta-analysis of prospective cohort studies.The international journal of behavioral nutrition and physical activity · 2024Pooled it
- Effects of Cardiovascular Disease Risk Factors, Musculoskeletal Health, and Physical Fitness on Occupational Performance in Firefighters-A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Prior exercise training and experimental myocardial infarction: A systematic review and meta-analysis.Clinics (Sao Paulo, Brazil) · 2020Pooled it
- Experiences of mobile health in promoting physical activity: A qualitative systematic review and meta-ethnography.PloS one · 2018Pooled it
- Trial
- A Confirmatory Factory Analysis of the Exercise Sensitivity Questionnaire (ESQ).Journal of cardiopulmonary rehabilitation and prevention · 2025Trial
- Effects of vitamin D, omega-3 and a simple strength exercise programme in cardiovascular disease prevention: The DO-HEALTH randomized controlled trial.The journal of nutrition, health & aging · 2024Trial
- The UP150: A Multifactorial Environmental Intervention to Promote Employee Physical and Mental Well-Being.International journal of environmental research and public health · 2022Trial
- Moderate endurance and muscle training is beneficial and safe in patients with quiescent or mildly active Crohn's disease.United European gastroenterology journal · 2020Trial
- Effects of prescribed aerobic exercise volume on physical activity and sedentary time in postmenopausal women: a randomized controlled trial.The international journal of behavioral nutrition and physical activity · 2018Trial
- Preliminary Efficacy of an Emotion Regulation Intervention on Physical Activity and Depressive and Anxious Symptoms in Individuals in Cardiac Rehabilitation.The Journal of cardiovascular nursingTrial
- Burden of cardiovascular disease in Brazil, 1996-2023: a retrospective descriptive study of the epidemiology and impact on public healthcare.Lancet regional health. Americas · 2027Article
- Pose2met: a unified spatiotemporal framework for 3D human pose estimation and energy expenditure estimation.Health information science and systems · 2026Article
- Just-in-Time Adaptive Interventions to Reduce Sedentary Behavior and Promote Physical Activity in Patients With Chronic Disease: Scoping Review.JMIR mHealth and uHealth · 2026Article
- Dose-dependent effects and mechanisms of exercise-like stimulation on cardiac injury and contractile function: outcomes of the MICRO-ATHLETE study.Basic research in cardiology · 2026Article
- Association between physical activity and mortality in postmenopausal women: evidence from NHANES 2007-2018.BMC women's health · 2026Article
- Article
- Psychosocial moderators of the effect of lifestyle interventions in primary prevention of cardiovascular disease: a scoping review.BMC public health · 2025Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although the observed progress in the cardiovascular disease treatment, the incidence of new and recurrent coronary artery disease remains elevated and constitutes the leading cause of death in the developed countries. Three-quarters of deaths due to cardiovascular diseases could be prevented with adequate changes in lifestyle, including increased daily physical activity. New evidence confirms that there is an inverse dose-response relationship between physical activity and cardiovascular disease and mortality risk. However, participation in moderate to vigorous physical activity may not fully attenuate the independent effect of sedentary activities on increased risk for cardiovascular diseases. Physical activity also plays an important role in secondary prevention of cardiovascular diseases by reducing the impact of the disease, slowing its progress and preventing recurrence. Nonetheless, most of eligible cardiovascular patients still do not benefit from secondary prevention/cardiac rehabilitation programs. The present review draws attention to the importance of physical activity in the primary and secondary prevention of cardiovascular diseases. It also addresses the mechanisms by which physical activity and regular exercise can improve cardiovascular health and reduce the burden of the disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.