ArticleFrontiers in human neuroscience2016
Melodic Intonation Therapy in Chronic Aphasia: Evidence from a Pilot Randomized Controlled Trial.
Article in Frontiers in human neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 9 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 9 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- Speech therapy for poststroke aphasia: a network meta-analysis of randomized controlled trials.PeerJ · 2026Pooled it
- Music-based interventions for nonfluent aphasia: A systematic review of randomized control trials.Annals of the New York Academy of Sciences · 2025Pooled it
- Neurologic music therapy for non-fluent aphasia: a systematic review and meta-analysis of randomized controlled trials.Frontiers in neurology · 2024Pooled it
- Melodic Intonation Therapy for aphasia: A multi-level meta-analysis of randomized controlled trials and individual participant data.Annals of the New York Academy of Sciences · 2022Pooled it
- Pooled it
- The effect of music therapy on language recovery in patients with aphasia after stroke: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Pooled it
- Melodic Intonation Therapy on Non-fluent Aphasia After Stroke: A Systematic Review and Analysis on Clinical Trials.Frontiers in neuroscience · 2021Pooled it
- Melodic Intonation Therapy for Post-stroke Non-fluent Aphasia: Systematic Review and Meta-Analysis.Frontiers in neurology · 2021Pooled it
- Effects of Music Therapy on Aphasia and Cognition of Patients with Post-stroke: A Systematic Review and Meta-analysis.Noise & healthPooled it
- Effects of Temporal Expectancy on Motor Control and Cognitive Processes Supporting Speech Production.Brain sciences · 2026Article
- The Use of Neurologic Music Therapy in Post-Stroke Aphasia Recovery: A Case Report on Linguistic Improvements and fMRI Correlates.Journal of clinical medicine · 2025Article
- A targeted review of prosodic production in agrammatic aphasia.Neuropsychological rehabilitation · 2025Review
- Treatment of aphasia in linguistically diverse populations: current and future directions.Frontiers in psychology · 2025Review
- Cognitive Crescendo: How Music Shapes the Brain's Structure and Function.Brain sciences · 2023Review
- Therapies and Challenges in the Post-Stroke Aphasia Rehabilitation Arena: Current and Future Prospects.Medicina (Kaunas, Lithuania) · 2023Review
- Melodic intonation therapy for non-fluent aphasia after stroke: A clinical pilot study on behavioral and DTI findings.iScience · 2023Article
- Clinical study of melodic intonation therapy combined with transcranial direct current stimulation for post-stroke aphasia: a single-blind, randomized controlled trial.Frontiers in neuroscience · 2023Article
- Effects of melodic intonation therapy in patients with chronic nonfluent aphasia.Annals of the New York Academy of Sciences · 2023Article
- A Review on Music Interventions for Frontotemporal Aphasia and a Proposal for Alternative Treatments.Biomedicines · 2022Review
- The relationship between entrainment dynamics and reading fluency assessed by sensorimotor perturbation.Experimental brain research · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Melodic Intonation Therapy (MIT) is a language production therapy for severely non-fluent aphasic patients using melodic intoning and rhythm to restore language. Although many studies have reported its beneficial effects on language production, randomized controlled trials (RCT) examining the efficacy of MIT are rare. In an earlier publication, we presented the results of an RCT on MIT in subacute aphasia and found that MIT was effective on trained and untrained items. Further, we observed a clear trend in improved functional language use after MIT: subacute aphasic patients receiving MIT improved considerably on language tasks measuring connected speech and daily life verbal communication. Here, we present the results of a pilot RCT on MIT in CLINICAL
trial registrationwww.ClinicalTrials.gov, identifier NTR 1961.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.