ArticleBMC oral health2016
Oral health and coronary heart disease.
Article in BMC oral health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Patient preferences and willingness to pay for dental services: a systematic review.BMC oral health · 2025Pooled it
- Influence of Natural Killer Cells and Natural Killer T Cells on Periodontal Disease: A Systematic Review of the Current Literature.International journal of molecular sciences · 2020Pooled it
- Trial
- Causal Bayesian network learning: application to the causal analysis of masticatory function and coronary heart disease in older adults.BMC medical informatics and decision making · 2026Article
- Latent class analysis of oral symptoms in stroke patients and exploration of associated.BMC oral health · 2025Article
- Oral Health Status, Behavior, and Knowledge of Patients with Cardiovascular Disease and Associated Risk Factors in Odisha: A Cross-Sectional Survey.Dentistry journal · 2025Article
- Insights from metagenomics into gut microbiome associated with acute coronary syndrome therapy.Frontiers in microbiology · 2024Article
- Unlocking Modifiable Risk Factors for Alzheimer's Disease: Does the Oral Microbiome Hold Some of the Keys?Journal of Alzheimer's disease : JAD · 2023Review
- Comparison of hematological parameters among chronic periodontitis patients and healthy individuals.Journal of advanced pharmaceutical technology & research · 2022Article
- Awareness and knowledge of oral manifestations in cardiovascular diseases among the general public.Journal of advanced pharmaceutical technology & research · 2022Article
- Salivary microbiota may predict the presence of esophageal squamous cell carcinoma.Genes & diseases · 2022Article
- Using a Systems Approach to Explore the Mechanisms of Interaction Between Severe Covid-19 and Its Coronary Heart Disease Complications.Frontiers in cardiovascular medicine · 2022Article
- Salivary Gland Dysfunction in Patients with Chronic Heart Failure Is Aggravated by Nitrosative Stress, as Well as Oxidation and Glycation of Proteins.Biomolecules · 2021Article
- Prevalence and Structure of Periodontal Disease and Oral Cavity Condition in Patients with Coronary Heart Disease (Prospective Cohort Study).International journal of general medicine · 2021Article
- Dental care during pregnancy based on the pregnancy risk assessment monitoring system in Utah.BMC oral health · 2019Article
- Transition of Bacterial Diversity and Composition in Tongue Microbiota during the First Two Years of Life.mSphere · 2019Article
- Characteristics of the Salivary Microbiota in Patients With Various Digestive Tract Cancers.Frontiers in microbiology · 2019Article
- Oral health status associated with sociodemographic factors of Nepalese schoolchildren: a population-based study.International dental journal · 2018Article
- Oral microbiome development during childhood: an ecological succession influenced by postnatal factors and associated with tooth decay.The ISME journal · 2018Article
- Presence of Dental Caries Is Associated with Food Insecurity and Frequency of Breakfast Consumption in Korean Children and Adolescents.Preventive nutrition and food science · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt is well documented that there is some correlation between poor oral health in the form of periodontal disease and coronary heart disease (CHD). It is unclear whether this correlation is due to a causal relationship or shared underlying disorder such as inflammation. A suitable integrated model of the CHD pathogenetic pathways relevant to periodontal disease may help to elucidate the association. Such a model is currently not available in literature.
methodsA previously developed integrated model of CHD was used to investigate potential pathogenetic pathways linking periodontal disease to CHD biomarkers.
resultsThe integrated model was created to provide insight into possible higher-order biological interactions underlying CHD and periodontal disease. In order to simplify these interactions a novel 'connection graph' was developed. It quantitatively illustrates the relationship between periodontal disease and various serological biomarkers of CHD. The pathogenesis of periodontitis shows various possible pathways which could link periodontitis to CHD pathogenesis.
conclusionAn integrated model of CHD was developed which provides a summary of the potential CHD effects of periodontal disease. Further research must refine and validate the model.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.