Evidence map›Paper›PMID 27846768›Full record

ArticleRenal failure2017

Olive oil abrogates acrylamide induced nephrotoxicity by modulating biochemical and histological changes in rats.

Imen Ghorbel, Awatef Elwej, Nesrine Fendri, Héla Mnif, Kamel Jamoussi, Tahia Boudawara, Naziha Grati Kamoun, Najiba Zeghal

Open access · goldAbstract read
In one paragraph

Article in Renal failure, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 66 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Imen Ghorbela Animal Physiology Laboratory, Faculty of Sciences of Sfax , University of Sfax , Sfax , Tunisia.
Awatef Elweja Animal Physiology Laboratory, Faculty of Sciences of Sfax , University of Sfax , Sfax , Tunisia.
Nesrine Fendrib Biochemistry Laboratory, CHU Hedi Chaker , University of Sfax , Sfax , Tunisia.
Héla Mnifc Anatomopathology Laboratory, CHU Habib Bourguiba , University of Sfax , Sfax , Tunisia.
Kamel Jamoussib Biochemistry Laboratory, CHU Hedi Chaker , University of Sfax , Sfax , Tunisia.
Tahia Boudawarac Anatomopathology Laboratory, CHU Habib Bourguiba , University of Sfax , Sfax , Tunisia.
Naziha Grati Kamound Technology & Quality Research Unit , Olive Tree Institute, University of Sfax , Sfax , Tunisia.
Najiba Zeghala Animal Physiology Laboratory, Faculty of Sciences of Sfax , University of Sfax , Sfax , Tunisia.
University of Sfax · TNHopital Universitaire Hedi Chaker · TNHopital Universitaire Habib Bourguiba · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acrylamide (ACR) is one of the most important contaminants occurring in foods heated at high temperatures. The aim of this study is to investigate the protective efficacy of extra virgin olive oil (EVOO), a main component of the Mediterranean diet, against nephrotoxicity induced by ACR. Rats have received by gavage during 21 days either ACR (40 mg/kg body weight) or ACR-associated with EVOO (300 μl) or only EVOO (300 μl). Acrylamide induced nephrotoxicity as evidenced by an increase in malondialdehyde (MDA), hydrogen peroxide (H

Indexed as

AcrylamideAnimalsAntioxidantsCatalaseDietary SupplementsFemaleGlutathioneGlutathione PeroxidaseHydrogen PeroxideKidneyKidney DiseasesL-Lactate DehydrogenaseMalondialdehydeOlive OilOxidative StressRandom AllocationAcrylamideAntioxidantsCatalaseGlutathioneGlutathione PeroxidaseHydrogen PeroxideL-Lactate DehydrogenaseMalondialdehydeOlive OilSuperoxide DismutaseAcrylamideantioxidant statusextra virgin olive oilnephrotoxicityrats

Identifiers

PMID27846768
PMCPMC6014333
OpenAlexW2553349388

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.