ReviewScience (New York, N.Y.)2016
Going global by adapting local: A review of recent human adaptation.
Review in Science (New York, N.Y.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 173 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
173 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Human genetic diversity across South Asian populations: A systematic review and meta-analysis.Medicine · 2025Pooled it
- Systematic analysis of population studies performed with the ForenSeq™ DNA Signature Prep kit.Journal of forensic sciences · 2025Pooled it
- Ancient DNA and Human Physiology.Physiology (Bethesda, Md.) · 2026Review
- Aberrant one-carbon metabolism and ancestral genetics underlie edematous severe acute malnutrition.Nature communications · 2026Article
- Accelerated Evolution of Context-Dependent Gene Expression in Primate Immune Cells.bioRxiv : the preprint server for biology · 2026Article
- Two Genetically Distinct Lineages in Galician Populations of the Three-Spined Stickleback (Ecology and evolution · 2026Article
- The landscape of human genomic diversity.BMC biology · 2026Article
- Article
- Pathogenic variation distribution of ACMG 3.2 list genes in 11 ethnic groups in southwest China.BMC genomics · 2026Article
- Bringing environment back into human evolution: why human genetics needs genome-environment association studies.Human genetics · 2026Review
- A century of theories of balancing selection.Biological reviews of the Cambridge Philosophical Society · 2026Review
- Article
- Immune gene diversity and STING1 variants in shaping cancer immunity across different genetic ancestry populations.Cell reports · 2026Article
- Ancient genomes give insight into 160,000 years of East Asian population dynamics and biological adaptation.Genome biology · 2025Review
- Revisiting the Evolution of Lactase Persistence: Insights from South Asian Genomes.bioRxiv : the preprint server for biology · 2025Article
- How Everything Is Connected to Everything Else - Population-Specific Connections between Adaptive Evolution, Disease Susceptibility, and Drug Responsiveness.Advanced genetics (Hoboken, N.J.) · 2025Article
- TheScience (New York, N.Y.) · 2025Article
- Molecular Genetic Basis of Reproductive Fitness in Tibetan Sheep on the Qinghai-Tibet Plateau.Genes · 2025Article
- Article
- A map of blood regulatory variation in South Africans enables GWAS interpretation.Nature genetics · 2025Article
113 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The spread of modern humans across the globe has led to genetic adaptations to diverse local environments. Recent developments in genomic technologies, statistical analyses, and expanded sampled populations have led to improved identification and fine-mapping of genetic variants associated with adaptations to regional living conditions and dietary practices. Ongoing efforts in sequencing genomes of indigenous populations, accompanied by the growing availability of "-omics" and ancient DNA data, promises a new era in our understanding of recent human evolution and the origins of variable traits and disease risks.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.