Evidence map›Paper›PMID 27846255›Full record

ArticlePloS one2016

Policies on Conflicts of Interest in Health Care Guideline Development: A Cross-Sectional Analysis.

Cristina Morciano, Vittorio Basevi, Carla Faralli, Michele Hilton Boon, Sabina Tonon, Domenica Taruscio

Abstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
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  8. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Article
  9. Conflicts of Interest in Inflammatory Bowel Disease Articles on UpToDate.Journal of the Canadian Association of Gastroenterology · 2021
    Article
  10. Managing conflicts of interest in the development of health guidelines.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Article
  11. Conflicts of interest in medicine: a never-ending story.Internal and emergency medicine · 2020
    Article
  12. Conflict of interest disclosure: striking a balance?The European journal of health economics : HEPAC : health economics in prevention and care · 2019
    Article
  13. Academic conflict of interest.Intensive care medicine · 2019
    Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cristina MorcianoCentro Nazionale Malattie Rare, Istituto Superiore di Sanità, Rome, Italy.
Vittorio BaseviCentro di Documentazione sulla Salute Perinatale e Riproduttiva, Servizio assistenza distrettuale, medicina generale, pianificazione e sviluppo dei servizi sanitari, Regione Emilia-Romagna, Bologna, Italy.
Carla FaralliServizio Informatico, Documentazione, Biblioteca e Attività Editoriali, Istituto Superiore di Sanità, Rome, Italy.
Michele Hilton BoonMRC/CSO Social and Public Health Sciences Unit, University of Glasgow, Glasgow, United Kingdom.
Sabina TononFormerly Centro Nazionale Malattie Rare, Istituto Superiore di Sanità, Rome, Italy.
Domenica TaruscioCentro Nazionale Malattie Rare, Istituto Superiore di Sanità, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess whether organisations that develop health care guidelines have conflict of interest (COI) policies and to review the content of the available COI policies.

methodsSurvey and content analysis of COI policies available in English, French, Spanish, and Italian conducted between September 2014 and June 2015. A 24-item data abstraction instrument was created on the basis of guideline development standards.

resultsThe survey identified 29 organisations from 19 countries that met the inclusion criteria. From these organisations, 19 policies were eligible for inclusion in the content analysis. Over one-third of the policies (7/19, 37%) did not report or did not clearly report whether disclosure was a prerequisite for membership of the guideline panel. Strategies for the prevention of COI such as divestment were mentioned by only two organisations. Only 21% of policies (4/19) used criteria to determine whether an interest constitutes a COI and to assess the severity of the risk imposed.

conclusionsThe finding that some organisations, in contradiction of widely available standards, still do not have COI policies publicly available is concerning. Also troubling were the findings that some policies did not clearly report critical steps in obtaining, managing and communicating disclosure of relationships of interest. This in addition to the variability encountered in content and accessibility of COI policies may cause confusion and distrust among guideline users. It is in the interest of guideline users and developers to design an agreed-upon, comprehensive, clear, and accessible COI policy.

Indexed as

Conflict of InterestCross-Sectional StudiesDisclosureHealth Care SectorHealth PolicyHumansInternational CooperationPractice Guidelines as Topic

Identifiers

PMID27846255
PMCPMC5113001

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.