Evidence map›Paper›PMID 27845743›Full record

ArticleToxins2016

A Structure Identification and Toxicity Assessment of the Degradation Products of Aflatoxin B₁ in Peanut Oil under UV Irradiation.

Jin Mao, Bing He, Liangxiao Zhang, Peiwu Li, Qi Zhang, Xiaoxia Ding, Wen Zhang

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
17.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 141 citations in OpenAlex.

  1. Article
  2. Biodegradation of aflatoxin in dried figs.World journal of microbiology & biotechnology · 2025
    Article
  3. Combined UV and Formic Acid Treatment SuppressesFoods (Basel, Switzerland) · 2025
    Article
  4. Toxics · 2025
    Article
  5. Article
  6. Review
  7. Aflatoxins in Peanut (ACS omega · 2024
    Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Detecting Aflatoxin BMolecules (Basel, Switzerland) · 2022
    Article
  13. Review
  14. Conventional and non-conventional disinfection methods to prevent microbial contamination in minimally processed fruits and vegetables.Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire · 2022
    Review
  15. Article
  16. Article
  17. Fungi Occurrence in Ready-to-Eat Hazelnuts (Frontiers in microbiology · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jin MaoOil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China. maojin106@whu.edu.cn.
Bing HeOil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China. xinxianghebing@163.com.
Liangxiao ZhangOil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China. liangxiao_zhang@126.com.
Peiwu LiOil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China. peiwuli@oilcrops.cn.
Qi ZhangOil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China. zhangqi521x@126.com.
Xiaoxia DingOil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China. dingdin2355@sina.com.
Wen ZhangOil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China. zhangwen@oilcrops.cn.
Chinese Academy of Agricultural Sciences · CNOil Crops Research Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aflatoxins, a group of extremely hazardous compounds because of their genotoxicity and carcinogenicity to human and animals, are commonly found in many tropical and subtropical regions. Ultraviolet (UV) irradiation is proven to be an effective method to reduce or detoxify aflatoxins. However, the degradation products of aflatoxins under UV irradiation and their safety or toxicity have not been clear in practical production such as edible oil industry. In this study, the degradation products of aflatoxin B₁ (AFB₁) in peanut oil were analyzed by Ultra Performance Liquid Chromatograph-Thermo Quadrupole Exactive Focus mass spectrometry/mass spectrometry (UPLC-TQEF-MS/MS). The high-resolution mass spectra reflected that two main products were formed after the modification of a double bond in the terminal furan ring and the fracture of the lactone ring, while the small molecules especially nitrogen-containing compound may have participated in the photochemical reaction. According to the above results, the possible photodegradation pathway of AFB₁ in peanut oil is proposed. Moreover, the human embryo hepatocytes viability assay indicated that the cell toxicity of degradation products after UV irradiation was much lower than that of AFB₁, which could be attributed to the breakage of toxicological sites. These findings can provide new information for metabolic pathways and the hazard assessment of AFB₁ using UV detoxification.

Indexed as

Ultraviolet RaysAflatoxin B1Cell LineCell SurvivalFood ContaminationHepatocytesHumansPeanut OilPhotolysisPlant OilsAflatoxin B1Peanut OilPlant Oilsaflatoxin B1cell viabilityfuran ringsphotodegradation productTQEF-MS/MS

Identifiers

PMID27845743
PMCPMC5127128
OpenAlexW2557007475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.