Evidence map›Paper›PMID 27845566›Full record

ArticleThe British journal of radiology2017

The potential predictive value of MRI and PET-CT in mucinous and nonmucinous rectal cancer to identify patients at high risk of metastatic disease.

Brunella Barbaro, Lucia Leccisotti, Fabio M Vecchio, Marialuisa Di Matteo, Teresa Serra, Marco Salsano, Andrea Poscia, Claudio Coco, Roberto Persiani, Sergio Alfieri and 4 more

Abstract readComparative Study
In one paragraph

Article in The British journal of radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
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  5. Importance of tumor subtypes in cancer imaging.European journal of radiology open · 2022
    Review
  6. Diagnostic value of [Frontiers in oncology · 2022
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Mucinous rectal cancer: concepts and imaging challenges.Abdominal radiology (New York) · 2019
    Review
  15. The role ofBMC cancer · 2019
    Article
  16. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Brunella Barbaro1 Department of Bioimaging and Radiological Sciences, Catholic University of Sacred Heart, Agostino Gemelli Hospital, Rome, Italy.
Lucia Leccisotti1 Department of Bioimaging and Radiological Sciences, Catholic University of Sacred Heart, Agostino Gemelli Hospital, Rome, Italy.
Fabio M Vecchio2 Department of Pathology, Catholic University of Sacred Heart, Agostino Gemelli Hospital, Rome, Italy.
Marialuisa Di Matteo1 Department of Bioimaging and Radiological Sciences, Catholic University of Sacred Heart, Agostino Gemelli Hospital, Rome, Italy.
Teresa Serra1 Department of Bioimaging and Radiological Sciences, Catholic University of Sacred Heart, Agostino Gemelli Hospital, Rome, Italy.
Marco Salsano1 Department of Bioimaging and Radiological Sciences, Catholic University of Sacred Heart, Agostino Gemelli Hospital, Rome, Italy.
Andrea Poscia4 Department of Hygiene, Catholic University of Sacred Heart, Agostino Gemelli Hospital, Rome, Italy.
Claudio Coco3 Department of Surgery, Catholic University of Sacred Heart, Agostino Gemelli Hospital, Rome, Italy.
Roberto Persiani3 Department of Surgery, Catholic University of Sacred Heart, Agostino Gemelli Hospital, Rome, Italy.
Sergio Alfieri3 Department of Surgery, Catholic University of Sacred Heart, Agostino Gemelli Hospital, Rome, Italy.
Maria Antonietta Gambacorta1 Department of Bioimaging and Radiological Sciences, Catholic University of Sacred Heart, Agostino Gemelli Hospital, Rome, Italy.
Vincenzo Valentini1 Department of Bioimaging and Radiological Sciences, Catholic University of Sacred Heart, Agostino Gemelli Hospital, Rome, Italy.
Alessandro Giordano1 Department of Bioimaging and Radiological Sciences, Catholic University of Sacred Heart, Agostino Gemelli Hospital, Rome, Italy.
Lorenzo Bonomo1 Department of Bioimaging and Radiological Sciences, Catholic University of Sacred Heart, Agostino Gemelli Hospital, Rome, Italy.
Agostino Gemelli University Polyclinic · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo correlate imaging parameters from baseline MRI diffusion-weighted imaging (DWI) and fludeoxyglucose (FDG) positron emission tomography (PET)-CT with synchronous and metachronous metastases in mucinous carcinoma (MC) and non-mucinous carcinoma (NMC) rectal cancer.

methods111 patients with extraperitoneal locally advanced rectal cancer, who underwent pelvic MRI, DWI and FDG PET-CT, were stratified into MC (n = 23) and NMC (n = 88). We correlated adverse morphologic features on MRI [mT4, mesorectal fascia involvement, extramural venous invasion (mEMVI), mN2] and quantitative imaging parameters [minimum apparent diffusion coefficient (ADC

resultsThe percentage of mucin measured by MRI correlates with that quantified by histology. On multivariate analysis, the synchronous metastases were correlated with mEMVI [odds ratio (OR) = 21.48, p < 0.01] and low ADC

conclusionmEMVI could identify patients with NMC, who are at high risk of synchronous metastases. The MC group is at a high risk of developing metachronous metastases. Advances in knowledge: Patients at high risk of metastases are more likely to benefit from more aggressive neoadjuvant therapy.

Indexed as

Adenocarcinoma, MucinousAdultAgedAged, 80 and overChemoradiotherapyCohort StudiesDiffusion Magnetic Resonance ImagingDisease-Free SurvivalFemaleFluorodeoxyglucose F18HumansKaplan-Meier EstimateMaleMiddle AgedMultimodal ImagingNeoplasm InvasivenessFluorodeoxyglucose F18

Identifiers

PMID27845566
PMCPMC5605010
OpenAlexW2549733719

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.