ArticleScientific reports2016
Two-stage (photoautotrophy and heterotrophy) cultivation enables efficient production of bioplastic poly-3-hydroxybutyrate in auto-sedimenting cyanobacterium.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 110 citations in OpenAlex.
- Interfacial Engineering Using Algal Biomolecules for Oil Pollution Mitigation.Environmental microbiology · 2026Review
- A novel recombinant PHB production platform in filamentous cyanobacteria avoiding nitrogen starvation while preserving cell viability.Microbial cell factories · 2025Article
- Characterization of Microalgae Biomass-Based Composites Obtained through Rotational Molding.Polymers · 2024Article
- Review
- Erythromycin mediates co-flocculation between cyanobacterium Synechocystis sp. PCC 6803 and filamentous fungi in liquid cultivation without organic compounds.Scientific reports · 2024Article
- Heterotrophy among Cyanobacteria.ACS omega · 2023Review
- Determination of Poly(3-hydroxybutyrate) Content in CyanobacteriumBio-protocol · 2023Article
- Novel concepts and engineering strategies for heterologous expression of efficient hydrogenases in photosynthetic microorganisms.Frontiers in microbiology · 2023Review
- Systematizing Microbial Bioplastic Production for Developing Sustainable Bioeconomy: Metabolic Nexus Modeling, Economic and Environmental Technologies Assessment.Journal of polymers and the environment · 2023Review
- Microalgal Biorefinery Concepts' Developments for Biofuel and Bioproducts: Current Perspective and Bottlenecks.International journal of molecular sciences · 2022Review
- Cyanobacteria as a Promising Alternative for Sustainable Environment: Synthesis of Biofuel and Biodegradable Plastics.Frontiers in microbiology · 2022Review
- Algal bioplastics: current market trends and technical aspects.Clean technologies and environmental policy · 2022Review
- Low Crystallinity of Poly(3-Hydroxybutyrate-co-3-Hydroxyvalerate) Bioproduction by Hot Spring CyanobacteriumPlants (Basel, Switzerland) · 2021Article
- Bioplastic Production from Microalgae: A Review.International journal of environmental research and public health · 2020Review
- Environmental Regulation of PndbA600, an Auto-Inducible Promoter for Two-Stage Industrial Biotechnology in Cyanobacteria.Frontiers in bioengineering and biotechnology · 2020Article
- Preparation of cyanobacteria-enhanced poly(vinyl)alcohol-based films with resistance to blue-violet light / red light and water.PloS one · 2020Article
- Utilization of shrimp wastewater for poly-β-hydroxybutyrate production byBiotechnology reports (Amsterdam, Netherlands) · 2019Article
- Disruption of cyanobacterial γ-aminobutyric acid shunt pathway reduces metabolites levels in tricarboxylic acid cycle, but enhances pyruvate and poly(3-hydroxybutyrate) accumulation.Scientific reports · 2019Article
- Bioprocess Engineering Aspects of Sustainable Polyhydroxyalkanoate Production in Cyanobacteria.Bioengineering (Basel, Switzerland) · 2018Review
- Novel quantitative insights into carbon sources for synthesis of poly hydroxybutyrate in Synechocystis PCC 6803.Photosynthesis research · 2018Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sustainable production of bioplastics by heterotrophic microbes has been restricted by the limited resources of organic substrates and the energy required for biomass harvest. Here, the easy-to-harvest cyanobacterium (Chlorogloea fritschii TISTR 8527), from which the biomass instantaneously settled to the bottom of liquid culture, was utilized to produce poly-3-hydroxybutyrate (PHB) using a two-stage cultivation strategy. The cells were first pre-grown under normal photoautotrophy to increase their biomass and then recultivated under a heterotrophic condition with a single organic substrate to produce the product. Through optimization of this two-stage cultivation, the mass conversion efficiency of acetate substrate to PHB was obtained at 51 ± 7% (w/w), the comparable level to the theoretical biochemical conversion efficiency of acetate to PHB. This two-stage cultivation that efficiently converted the substrate to the product, concurrent with a reduced culture biomass, may be applicable for the production of other biopolymers by cyanobacteria.
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