Evidence map›Paper›PMID 27845396›Full record

ArticleScientific reports2016

First steps to define murine amniotic fluid stem cell microenvironment.

E Bertin, M Piccoli, C Franzin, G Spiro, S Donà, A Dedja, F Schiavi, E Taschin, P Bonaldo, P Braghetta and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

E BertinStem Cells and Regenerative Medicine Lab, Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padova, Italy.
M PiccoliStem Cells and Regenerative Medicine Lab, Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padova, Italy.
C FranzinStem Cells and Regenerative Medicine Lab, Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padova, Italy.
G SpiroStem Cells and Regenerative Medicine Lab, Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padova, Italy.
S DonàDepartment of Molecular Medicine, University of Padova, Padova, Italy.
A DedjaDepartment of Cardiac, Thoracic and Vascular Sciences, University of Padova, Padova, Italy.
F SchiaviFamilial Cancer Clinic and Oncoendocrinology, Veneto Institute of Oncology, Padova, Italy.
E TaschinFamilial Cancer Clinic and Oncoendocrinology, Veneto Institute of Oncology, Padova, Italy.
P BonaldoDepartment of Molecular Medicine, University of Padova, Padova, Italy.
P BraghettaDepartment of Molecular Medicine, University of Padova, Padova, Italy.
P De CoppiStem Cells and Regenerative Medicine Section, Developmental Biology and Cancer Programme, UCL Institute of Child Health and Great Ormond Street Hospital, London, United Kingdom.
M PozzobonStem Cells and Regenerative Medicine Lab, Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padova, Italy.

Funding

Department of Health RP_2014-04-046
6 · The paper itself

Abstract

Stem cell niche refers to the microenvironment where stem cells reside in living organisms. Several elements define the niche and regulate stem cell characteristics, such as stromal support cells, gap junctions, soluble factors, extracellular matrix proteins, blood vessels and neural inputs. In the last years, different studies demonstrated the presence of cKit

Indexed as

Amniotic FluidMouse Embryonic Stem CellsAnimalsAntigens, DifferentiationFemaleMiceMice, KnockoutStem Cell NicheAntigens, Differentiation

Identifiers

PMID27845396
PMCPMC5109045

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.