Evidence map›Paper›PMID 27844170›Full record

ArticleJournal of industrial microbiology & biotechnology2017

Comparative analysis of the Corynebacterium glutamicum transcriptome in response to changes in dissolved oxygen levels.

Xiuxia Liu, Sun Yang, Fen Wang, Xiaofeng Dai, Yankun Yang, Zhonghu Bai

RetractedAbstract readRetracted Publication
PubMed Publisher
In one paragraph

Article in Journal of industrial microbiology & biotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Xiuxia LiuNational Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi, 214122, China.
Sun YangNational Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi, 214122, China.
Fen WangNational Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi, 214122, China.
Xiaofeng DaiNational Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi, 214122, China.
Yankun YangNational Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi, 214122, China. yangyankun@jiangnan.edu.cn.
Zhonghu BaiNational Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi, 214122, China. baizhonghu@jiangnan.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dissolved oxygen (DO) level of a culture of Corynebacterium glutamicum (C. glutamicum) in a bioreactor has a significant impact on the cellular redox potential and the distribution of energy and metabolites. In this study, to gain a deeper understanding of the effects of DO on the metabolism of C. glutamicum, we sought to systematically explore the influence of different DO concentrations on genetic regulation and metabolism through transcriptomic analysis. The results revealed that after 20 h of fermentation, oxygen limitation enhanced the glucose metabolism, pyruvate metabolism and carbon overflow, and restricted NAD

Indexed as

TranscriptomeBioreactorsCarbonCitric Acid CycleCorynebacterium glutamicumFermentationGene Expression ProfilingGlucoseGlyoxylatesIndustrial MicrobiologyOxygenPyruvic AcidRNA, BacterialSequence Analysis, RNACarbonGlucoseGlyoxylatesglyoxylic acidOxygenPyruvic AcidRNA, BacterialBioprocessCorynebacterium glutamicumDissolved oxygenMetabolismTranscriptome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.