ArticleEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2017
Clinical and epidemiological differences between implant-associated and implant-free orthopaedic infections.
Article in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Biomaterial-Based Scaffolds as Carriers of Topical Antimicrobials for Bone Infection Prophylaxis.Polish journal of microbiology · 2025Review
- Clinical and epidemiological differences in staphylococcal osteoarticular infections: insights for developing hospital-based infection control interventions.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025Article
- Therapy for Non-Diabetic Foot Infections After Orthopedic Foot and Ankle Surgery: The Duration of Post-Debridement Antibiotic Treatment Does Not Alter Failure Risk.Life (Basel, Switzerland) · 2024Article
- Article
- A Rare Pathogen of Bones and Joints: A Systematic Review of Osteoarticular Infections Caused byJournal of clinical medicine research · 2023Review
- Article
- Biofilm formation and inflammatory potential ofFrontiers in microbiology · 2022Article
- The epidemiology of fracture-related infections in Germany.Scientific reports · 2021Article
- Osteoarticular infections: a specific program for older patients?Aging clinical and experimental research · 2021Review
- Interleukin-1β and tumor necrosis factor are essential in controlling an experimental orthopedic implant-associated infection.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2020Article
- Should antibiotic prophylaxis before orthopedic implant surgery depend on the duration of pre-surgical hospital stay?Antimicrobial resistance and infection control · 2018Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAlthough there have been many publications regarding the risk factors for implant-associated orthopaedic infections, none have investigated how clinical presentations and epidemiology may differ between infections with and without osteosynthetic material.
methodsWe pooled clinical data from several databases of adult patients with orthopaedic infections hospitalized at Geneva University Hospitals from January 2004 to December 2014.
resultsAmong 2740 episodes of orthopaedic infections, 76% were implant-free osteoarticular or soft tissue infections. Among the 665 (24% of the total episodes) infections that involved osteosynthetic material, 319 (49%) were total joint arthroplasties, 143 single plates, and 50 single nails. The remainders were mixed implant infections, pins, wires, screws, cerclages or spondylodeses. The implant-associated, compared to the implant-free, infections were significantly more frequently associated with female sex, older age, bacteraemia and skin commensal infections, e.g. coagulase-negative staphylococci, corynebacteria or propionibacteria. In contrast, implant-associated infections were significantly less frequently associated with immune suppression, abscess formation, infections due to Staphylococcus aureus or streptococci, polymicrobial pathogens and foot infections. The serum CRP levels at admission were similar (median 82 vs. 75 mg/L).
conclusionsCompared to implant-free infections, implant-associated orthopaedic infections are more likely monomicrobial, bacteraemic and due to skin commensals. They involve more often female and older patients, but are less often associated with immune suppression, abscess formation and foot infections.
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