ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2017
Gait speed and one-leg standing time each add to the predictive ability of FRAX.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Association between self-rated health and the risk of hip fracture and mortality in a cohort of older women during a 10-year follow-up.PloS one · 2021Trial
- Reduced walking speed at discharge predicts mortality after clinical osteoporotic vertebral fracture: A retrospective cohort study.Archives of osteoporosis · 2026Article
- One-leg standing test in older adults with left-right differences; does dominant foot distinctly decide?BMC musculoskeletal disorders · 2025Article
- Plantar cutaneous sensation is independently associated with postural balance and lower limb motor function in older adults: the Shizuoka study.European geriatric medicine · 2025Article
- Levels of parathyroid hormone and IGF binding protein 1 and associations with mortality and hip fractures in older women.Scientific reports · 2024Article
- Muscle parameters in fragility fracture risk prediction in older adults: A scoping review.Journal of cachexia, sarcopenia and muscle · 2024Article
- Performance of FRAX in older adults with frailty: the Framingham Heart Study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024Article
- One-leg standing time is a simple measure for loss of skeletal muscle mass and fat deposition in muscle: the J-SHIPP study.Aging clinical and experimental research · 2024Article
- Risk factors for osteoporotic hip fracture among community-dwelling older adults: a real-world evidence study.Advances in rheumatology (London, England) · 2024Article
- AI algorithms for accurate prediction of osteoporotic fractures in patients with diabetes: an up-to-date review.Journal of orthopaedic surgery and research · 2023Review
- Changes in physical activity levels and relationship to balance performance, gait speed, and self-rated health in older Swedish women: a longitudinal study.Aging clinical and experimental research · 2022Article
- Association of sarcopenia with incident osteoporosis: a prospective study of 168,682 UK biobank participants.Journal of cachexia, sarcopenia and muscle · 2021Article
- Detecting subtle mobility changes among older adults: the Quantitative Timed Up and Go test.Aging clinical and experimental research · 2021Article
- Risk factors for incident vertebral fractures in osteoporosis pharmacotherapy: a 2-year, prospective, observational study.Journal of bone and mineral metabolism · 2021Observational
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- Effects of dietary supplementation with milk fat globule membrane on the physical performance of community-dwelling Japanese adults: a randomised, double-blind, placebo-controlled trial.Journal of nutritional science · 2018Article
- Dysmobility Syndrome and Risk of Mortality for Community-Dwelling Middle-Aged and Older Adults: The Nexus of Aging and Body Composition.Scientific reports · 2017Article
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6 authors.
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Abstract
Gait speed or one-leg standing time (OLST) as additional predictors in FRAX. Population 351 elderly women followed 10 years. Both could improve predictions. The area under curve (AUC) for FRAX is 0.59, OLST is 0.69 and gait speed is 0.71. The net reclassification index (NRI) for classification to highest risk quartile or lowest three quartiles was 0.24 for gait speed and non-significant for OLST.
introductionThe risk of falls and bone strength are two main determinants of hip fracture risk. The fracture risk assessment tool FRAX, however, lacks direct measures of fall risk
methodsA population-based sample of 351 women aged between 69 and 79 years were tested for one-leg standing time with eyes open and mean gait speed over a 15 + 15-m walk. Fracture and mortality data were obtained from health care registers.
resultsThe AUC for the receiver operating characteristic (ROC) increased from 0.61 to 0.71 when gait speed was added to FRAX. The AUC was 0.69 for OLST added to FRAX. The highest quartile of hip fracture risks according to FRAX had an absolute 10-year risk of ≥15%. The population was divided into one group with a hip fracture risk of ≥15% and one group with a fracture risk of <15%. NRI for addition of gait speed to FRAX was 0.24 (p = 0.023), while NRI was 0.08 (p = 0.544) for addition of OLST to FRAX.
conclusionGait speed tended to improve the predictive ability of FRAX more than OLST, but they both added value to FRAX.
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