ArticleeNeuro
Lithium-Responsive Seizure-Like Hyperexcitability Is Caused by a Mutation in the
Open access · goldAbstract read
In one paragraph
Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 28 citations in OpenAlex.
- Metabolic Alterations Induced by a Seizure-Causing Sodium Channel Mutation and their Partial Normalization by Dietary α-Linolenic Acid in Drosophila.Neurochemical research · 2026Article
- Automated identification of ataxia and convulsions in hyperexcitablebioRxiv : the preprint server for biology · 2025Article
- Effects of a Gain-of-Function Mutation in the Voltage-Gated Sodium Channel Gene, and of Dietary α-Linolenic Acid Supplementation, on Whole-Body Metabolism in Drosophila.Research square · 2025Article
- Effects of lithium on mortality and metabolite profiles in Drosophila lithium-inducible SLC6 transporter mutants.Environmental toxicology and pharmacology · 2025Article
- Automated identification of ataxia and convulsions in hyperexcitablemicroPublication biology · 2025Article
- Replication of seizure-suppressing effects of alpha-linolenic acid on themicroPublication biology · 2025Article
- Commensal bacteria exacerbate seizure-like phenotypes in Drosophila voltage-gated sodium channel mutants.Genes, brain, and behavior · 2024Article
- Glial expression of Drosophila UBE3A causes spontaneous seizures that can be modulated by 5-HT signaling.Neurobiology of disease · 2024Article
- Intense light unleashes male-male courtship behaviour in wild-typeOpen biology · 2023Article
- Dietary Supplementation with Milk Lipids Leads to Suppression of Developmental and Behavioral Phenotypes of Hyperexcitable Drosophila Mutants.Neuroscience · 2023Article
- Effects of lithium on aggression in Drosophila.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Article
- Efficient strategies based on behavioral and electrophysiological methods for epilepsy-related gene screening in theFrontiers in molecular neuroscience · 2023Article
- Article
- Review
- The gut-microbiota-brain axis in autism: what Drosophila models can offer?Journal of neurodevelopmental disorders · 2021Review
- Fly seizure EEG: field potential activity in theJournal of neurogenetics · 2021Article
- Reduced Function of the Glutathione S-Transferase S1 Suppresses Behavioral Hyperexcitability inG3 (Bethesda, Md.) · 2020Article
- Pyridox (am) ine 5'-phosphate oxidase deficiency induces seizures in Drosophila melanogaster.Human molecular genetics · 2019Article
- Milk-whey diet substantially suppresses seizure-like phenotypes ofJournal of neurogenetics · 2019Article
- Up-regulation of antioxidative proteins TRX1, TXNL1 and TXNRD1 in the cortex of PTZ kindling seizure model mice.PloS one · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Garrett A KaasInterdisciplinary Graduate Program in Genetics, University of Iowa , IA 52242, USA.ORCID 0000-0002-1916-975X
Junko KasuyaDepartment of Anesthesia, Carver College of Medicine, University of Iowa , IA 52242.
Patrick LansdonInterdisciplinary Graduate Program in Genetics, University of Iowa , IA 52242, USA.ORCID 0000-0002-9004-6138
Atsushi UedaDepartment of Biology, College of Liberal Arts and Sciences, University of Iowa , IA 52242.
Atulya IyengarInterdisciplinary Graduate Program in Neuroscience, University of Iowa , IA 52242.
Chun-Fang WuInterdisciplinary Graduate Program in Genetics, University of Iowa, IA 52242, USA; Department of Biology, College of Liberal Arts and Sciences, University of Iowa, IA 52242; Interdisciplinary Graduate Program in Neuroscience, University of Iowa, IA 52242.
Toshihiro KitamotoInterdisciplinary Graduate Program in Genetics, University of Iowa, IA 52242, USA; Department of Anesthesia, Carver College of Medicine, University of Iowa, IA 52242; Interdisciplinary Graduate Program in Neuroscience, University of Iowa, IA 52242.ORCID 0000-0003-0863-8466
University of Iowa · US
Funding
PREDOCTORAL TRAINING PROGRAM IN GENETICST32GM008629 · NIGMS · UNIVERSITY OF IOWA · PI EBERL, DANIEL F · 1997 to 2021
$4.1MInterdisciplinary Training Program in Pain ResearchT32NS045549 · NINDS · UNIVERSITY OF IOWA · PI KATHLEEN A SLUKA, Yuriy M Usachev · 2004 to 2026
$3.7MGenetic analysis of age-related functional decline of Drosophila NMJR01AG051513 · NIA · UNIVERSITY OF IOWA · PI WU, CHUN-FANG · 2015 to 2019
$1.9MStudies of genes involved in the lithium responsive neurological processesR01MH085081 · NIMH · UNIVERSITY OF IOWA · PI KITAMOTO, TOSHIHIRO · 2009 to 2013
$1.6MPlasticity of Neuronal Function and Form in DrosophilaR01GM088804 · NIGMS · UNIVERSITY OF IOWA · PI WU, CHUN-FANG · 2009 to 2012
$1.2MRole of the DSC1 family of cation channels in insect neurophysiology and neurotoxR01GM080255 · NIGMS · MICHIGAN STATE UNIVERSITY · PI DONG, KE, WU, CHUN-FANG · 2009 to 2012
$1.1MThe role of sodium channels in shaping neuronal circuit outputF31NS082001 · NINDS · UNIVERSITY OF IOWA · PI IYENGAR, ATULYA SRISUDARSHAN RAM · 2012 to 2014
$77kGenetic Analysis of Lithium-Responsive Neurological ProcessesF31MH081788 · NIMH · UNIVERSITY OF IOWA · PI KAAS, GARRETT A · 2009 to 2010
$37kNIA NIH HHS R01 AG051513NIGMS NIH HHS R01 GM080255NIGMS NIH HHS R01 GM088804NIGMS NIH HHS T32 GM008629NIMH NIH HHS F31 MH081788NIMH NIH HHS R01 MH085081NINDS NIH HHS F31 NS082001NINDS NIH HHS T32 NS045549
Abstract
PubMed holds no abstract for this paper.
Indexed as
MutationAnimalsAnimals, Genetically ModifiedAnticonvulsantsDrosophila melanogasterDrosophila ProteinsFemaleGene ExpressionLithium CompoundsMaleMembrane Transport ModulatorsMotor ActivityMusclesNeuronsPhenotypeSeizuresAnticonvulsantsDrosophila ProteinsLithium CompoundsMembrane Transport Modulatorspara protein, DrosophilaSodium ChannelsDrosophilalithiumneurogeneticsseizurevoltage-gated sodium channel
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.