ReviewFrontiers in bioengineering and biotechnology2016
Biomaterials and Nanotherapeutics for Enhancing Skin Wound Healing.
Review in Frontiers in bioengineering and biotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 126 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
126 citing papers in PubMed, 1 synthesis or guideline pooled it, 321 citations in OpenAlex.
- A Systematic Review and Meta-Analysis of Clinical Effectiveness and Safety of Hydrogel Dressings in the Management of Skin Wounds.Frontiers in bioengineering and biotechnology · 2019Pooled it
- Wound healing effects of topical Vitamin K: A randomized controlled trial.Indian journal of pharmacologyTrial
- Bioactive Hydrogels with D-Amino Acid RGD Mimics: A Therapeutic Strategy for Expeditious Infected Wound Closure.Advanced healthcare materials · 2026Article
- Multifunctional Prussian-Blue-Based Hydrogel for Photothermal Antibacterial and Infected Wound Regeneration.Polymers · 2026Article
- Article
- Comparative proteomic analysis of skin wound healing responses to biomaterial treatments identifies key pathways which govern differential regenerative outcomes.Biomaterials · 2026Article
- PLGA nanofibers carrying rhFGF1 for the effective treatment of skin wounds in diabetic mice.BMC biotechnology · 2026Article
- Apoptotic vesicles from endothelial cells promote endothelial progenitor cell differentiation and angiogenesis via miR-30a-5p mediated activation of the EGFR/PI3K/AKT/VEGF pathway.Stem cell research & therapy · 2026Article
- Dynamic, Reconfigurable, and Hierarchical Biosynthetic Composites via Collagen Self-Assembly within Highly Crowded Microgel Pastes.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Research progress of responsive electrospun dressings for precise monitoring and treatment of diabetic wounds.Burns & trauma · 2026Review
- Exploring New Horizons in Wound Healing: A Comprehensive Analysis.Recent advances in inflammation & allergy drug discovery · 2026Review
- Cotton gauze wound-dressing patches loaded with dapsone derivative and silver nanoparticles for promoting wound healingRSC advances · 2025Article
- Harnessing marine-derived materials for therapeutics innovations: Advances in biomaterials from the ocean.Materials today. Bio · 2025Review
- Porous Silicon Nanoparticle Hydrogel Formulation for Topical Delivery of Flightless I Neutralizing Antibody and Improved Diabetic Wound Healing.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Advanced wound healing with Stimuli-Responsive nanozymes: mechanisms, design and applications.Journal of nanobiotechnology · 2025Review
- Biocompatible nanostructured chitosan scaffolds for enhanced diabetic wound healing: Innovations and strategies.3 Biotech · 2025Review
- Aligned Electrospun PCL/PLA Nanofibers Containing Green-Synthesized CeOInternational journal of molecular sciences · 2025Article
- Poly(vinyl alcohol)/Gentamicin and Poly(vinyl alcohol)/Chitosan/Gentamicin: Promising Materials for Rapid Burn Wound Healing.Gels (Basel, Switzerland) · 2025Article
- Regenerative potential of graphene oxide-chitosan nanocomposite combined with fetal bovine serum on healing of full-thickness skin wound in rats.BMC veterinary research · 2025Article
- Well-regulated Dermal Regeneration Using Amnion-containing Scaffold in a Preclinical Study.Advanced pharmaceutical bulletin · 2025Article
66 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Wound healing is an intricate process that requires complex coordination between many cell types and an appropriate extracellular microenvironment. Chronic wounds often suffer from high protease activity, persistent infection, excess inflammation, and hypoxia. While there has been intense investigation to find new methods to improve cutaneous wound care, the management of chronic wounds, burns, and skin wound infection remain challenging clinical problems. Ideally, advanced wound dressings can provide enhanced healing and bridge the gaps in the healing processes that prevent chronic wounds from healing. These technologies have great potential for improving outcomes in patients with poorly healing wounds but face significant barriers in addressing the heterogeneity and clinical complexity of chronic or severe wounds. Active wound dressings aim to enhance the natural healing process and work to counter many aspects that plague poorly healing wounds, including excessive inflammation, ischemia, scarring, and wound infection. This review paper discusses recent advances in the development of biomaterials and nanoparticle therapeutics to enhance wound healing. In particular, this review focuses on the novel cutaneous wound treatments that have undergone significant preclinical development or are currently used in clinical practice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.