Evidence map›Paper›PMID 27843871›Full record

ArticleJournal of family medicine and primary care

Reversible ecchymosis and hyperpigmented lesions: A rare presentation of dietary Vitamin B12 deficiency.

Hans Raj Pahadiya, Manoj Lakhotia, Sukhdev Choudhary, Gopal Raj Prajapati, Sangeeta Pradhan

Registry-linked trialOpen access · goldAbstract readCase Reports
In one paragraph

Article in Journal of family medicine and primary care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06823999 (Effect of Vitamin C in the Prevention and Treatment for Bruises in Patients With Ischemic Stroke), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06823999 phase4not yet recruitingnot on this map

Effect of Vitamin C in the Prevention and Treatment for Bruises in Patients With Ischemic Stroke: A Double-blind Randomized Control Trial

TypeinterventionalSponsorChiayi Christian HospitalRan2025 to 2028Enrolled400ConditionsStroke, Bruises, Skin LesionsArmsAscorbic acid (Vitamin C), Normal Saline (Placebo)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. A Brief Review on Vitamin BInternational journal of molecular sciences · 2021
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hans Raj PahadiyaDepartment of Medicine, Dr. S.N. Medical College, Jodhpur, Rajasthan, India.
Manoj LakhotiaDepartment of Medicine, Dr. S.N. Medical College, Jodhpur, Rajasthan, India.
Sukhdev ChoudharyDepartment of Medicine, Dr. S.N. Medical College, Jodhpur, Rajasthan, India.
Gopal Raj PrajapatiDepartment of Medicine, Dr. S.N. Medical College, Jodhpur, Rajasthan, India.
Sangeeta PradhanDepartment of Medicine, Dr. S.N. Medical College, Jodhpur, Rajasthan, India.
Sarojini Naidu Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 40-year-old male presented because of generalized weakness, fatigability, and hyperpigmentation with ecchymosis, he was diagnosed to have dietary Vitamin B12 deficiency anemia. The hyperpigmentation and ecchymosis lesions resolved after Vitamin B12 supplementation. Beside hyperpigmented lesion on the skin, the presence of ecchymosis is a very rare manifestation of the disease. Thrombocytopenia in Vitamin B12 deficiency anemia rarely leads to ecchymosis.

Indexed as

EcchymosishyperpigmentationVitamin B12 deficiency

Identifiers

PMID27843871
PMCPMC5084591
OpenAlexW2537424116

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.