ReviewESMO open2016
Challenge of cancer in the elderly.
Review in ESMO open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
74 citing papers in PubMed, 1 synthesis or guideline pooled it, 153 citations in OpenAlex.
- Has a High Dose of Vitamin D3 Impacted Health Conditions in Older Adults?-A Systematic Review and Meta-Analysis Focusing on Dose 100,000 IU.Nutrients · 2024Pooled it
- Prioritisation of treatment goals among older patients with non-curable cancer: the OPTion randomised controlled trial in Dutch primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2020Trial
- Trial
- Clinical outcomes in older adults with advanced thyroid cancer.The oncologist · 2026Article
- Temporal trends in cardiac arrest and cancer-related mortality among adults in the United States, 1999-2023.Cardio-oncology (London, England) · 2026Article
- Aging modulation of the immune system and immunotherapy efficacy in cancer.Frontiers in immunology · 2026Review
- Causal Association Between Oral Microbiota and Major Salivary Gland Cancer: A Bidirectional Two-Sample Mendelian Randomization Study.Oral health & preventive dentistry · 2025Article
- Cancer and Aging Biomarkers: Classification, Early Detection Technologies and Emerging Research Trends.Biosensors · 2025Review
- Adaptation and Implementation of Self-System Therapy for Older Adults with Advanced Lung Cancer: Pilot Trial Results.Cancers · 2025Article
- Cross-Cultural Adaptation and Psychometric Properties of the Persian Version of the Spiritual Distress Scale (P-SDS) Among Older Adults with Cancer in Iran.Journal of religion and health · 2025Article
- Article
- Comparison of monotherapy and combination therapy for older patients with advanced biliary tract cancer: a retrospective study.BMC cancer · 2025Article
- Multidisciplinary management of N2 stage III non-small cell lung cancer: opportunities and challenges for radiation oncology.Translational lung cancer research · 2025Review
- Lung Cancer and Palliative Care Support: The Role of Social Determinants of Health for Older Adult Patients.Oncology nursing forum · 2024Article
- Global burden of cancer pattern in 2020 & prediction to 2040 among older adults.The Indian journal of medical research · 2024Article
- Efficacy and Safety of Docetaxel plus Ramucirumab for Patients with Pretreated Advanced or Recurrent Non-small Cell Lung Cancer: Focus on Older Patients.Targeted oncology · 2024Article
- Exploring the Language Used to Describe Older Patients at Multidisciplinary Cancer Conferences.Cancers · 2024Article
- Safety of flexible bronchoscopy and clinical course for elderly patients with suspected primary lung cancer.Thoracic cancer · 2024Article
- Geriatric Communication Skills Training Program for Oncology Healthcare Providers: a Secondary Analysis of Patient and Caregiver Outcomes.Journal of cancer education : the official journal of the American Association for Cancer Education · 2024Article
- Identity, Resilience and their Psychological Impact Among Older Adults with Cancer.Vertices (Duke University: 1991) · 2024Article
14 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite the sustained trend of decreasing overall cancer incidence, the number of elderly patients with cancer will considerably increase in the coming years, as the incidence of cancer is elevated 11-fold after the age of 65 years compared to adults up to 65 years. This soon-to-erupt tsunami of elderly patients with cancer requires adequate treatment, for which guidelines and evidence-based data are still scarce, given the longlasting under-representation of elderly patients with cancer in cancer trials. Older adults present not only with the physiological decreases of organ functions related to age, but also with an individual burden of comorbidities, other impairments and social factors that might impact on their potential for undergoing cancer care. Close collaboration with gerontologists and other health professionals to assess the personal resources and limitations of each person enables providing adequate therapy to elderly patients with cancer. There are promising achievements in each of the requirements listed, but a huge, holistic effort has still to be made.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.