ArticleBMJ open gastroenterology2016
Cachexia in cancer: what is in the definition?
Article in BMJ open gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07255001 (Monitoring Physical Function Changes in Patients With Pancreatic Ductal Adenocarcinoma), which is not on this map. Cited by 67 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Monitoring Physical Function Changes in Patients With Pancreatic Ductal Adenocarcinoma: Potential for Better Understanding of Treatment Trajectory and Survival
Who cites it
67 citing papers in PubMed, 4 syntheses or guidelines pooled it, 125 citations in OpenAlex.
- Prevalence of and Survival with Cachexia among Patients with Cancer: A Systematic Review and Meta-Analysis.Advances in nutrition (Bethesda, Md.) · 2024Pooled it
- The prognostic impact of pre-treatment cachexia in resectional surgery for oesophagogastric cancer: a meta-analysis and meta-regression.The British journal of surgery · 2023Pooled it
- Physical function endpoints in cancer cachexia clinical trials: Systematic Review 1 of the cachexia endpoints series.Journal of cachexia, sarcopenia and muscle · 2023Pooled it
- Predictive value of preoperative handgrip strength on postoperative outcomes in patients with gastrointestinal tumors: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Pooled it
- Differential response to targeted acupuncture by gender in patients with gastrointestinal cancer cachexia: secondary analysis of a randomized controlled trial.Acupuncture in medicine : journal of the British Medical Acupuncture Society · 2020Trial
- Prevalence of Cancer Cachexia Among Breast Cancer Patients in Pakistan, Assessed Using the Mini-CASCO Scoring System.Asian Pacific journal of cancer prevention : APJCP · 2026Observational
- A Comprehensive Analysis of Adverse Events Associated with HER2 Inhibitors Approved for Breast Cancer Using the FDA Adverse Event Report System (FAERS).Pharmaceuticals (Basel, Switzerland) · 2025Article
- Hallmarks of Cancer Cachexia: Sexual Dimorphism in Related Pathways.International journal of molecular sciences · 2025Review
- Diagnostic Criteria for Cancer-Associated Cachexia: Insights from a Multicentre Cohort Study.Journal of cachexia, sarcopenia and muscle · 2025Article
- Article
- Cancer cachexia and weight loss before CAR T-cell therapy for lymphoma are independently associated with poor outcomes.Blood advances · 2025Article
- Comparative Study on Associations Between Lung Cancer Prognosis and Diagnostic Criteria Set by the European Palliative Care Research Collaboration and the Asian Working Group for Cachexia.Thoracic cancer · 2025Article
- Severe Deficiency of Vitamin D and Anthracycline-Taxane Regimen are associated with Cachexia Following Breast Cancer Chemotherapy: A Single Center Assessment Using Two Consensus-Based Criteria.Asian Pacific journal of cancer prevention : APJCP · 2025Article
- Colorectal cancer prognosis based on dietary pattern using synthetic minority oversampling technique with K-nearest neighbors approach.Scientific reports · 2024Article
- "Metabolic fingerprints" of cachexia in lung cancer patients.European journal of nuclear medicine and molecular imaging · 2024Article
- Validity of the diagnostic criteria from the Asian Working Group for Cachexia in advanced cancer.Journal of cachexia, sarcopenia and muscle · 2024Article
- Malnutrition prevalence in cancer patients in Belgium: The ONCOCARE study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Observational
- Cross-species conserved miRNA as biomarker of radiation injury over a wide dose range using nonhuman primate model.PloS one · 2024Article
- Relationship between Survival Days, Cancer Cachexia, and Activities of Daily Living in Palliative Cancer Patients Undergoing Rehabilitation.Progress in rehabilitation medicine · 2024Article
- Predictors of efficacy of anamorelin in patients with non‑small cell lung cancer and cachexia: A retrospective study.Oncology letters · 2024Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
30 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to provide evidence-based results on differences in overall survival (OS) rate to guide the diagnosis of cancer cachexia.
designData collection and clinical assessment was performed every 3 months (5 visits): baseline data, muscle strength, nutritional and psychosocial status. 2 definitions on cachexia using different diagnostic criteria were applied for the same patient population. Fearon
resultsBased on the population of 167 patients who enrolled, 70% developed cachexia according to Fearon
conclusionThis study presents a correlation with prognosis in favour of Evans TRIAL REGISTRATION NUMBER: B300201112334.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.