Evidence map›Paper›PMID 27843551›Full record

ArticleBMJ open diabetes research & care2016

Economic aspects in the management of diabetes in Italy.

A Marcellusi, R Viti, P Sciattella, G Aimaretti, S De Cosmo, V Provenzano, G Tonolo, F S Mennini

Open access · goldAbstract read
In one paragraph

Article in BMJ open diabetes research & care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
11.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. An Analysis of the Distribution of Direct Cost of Diabetes Care in Selected Districts in Italy.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024
    Article
  5. Observational
  6. Healthcare Services for Undocumented Migrants: Organisation and Costs from the Italian NHS Perspective.International journal of environmental research and public health · 2022
    Article
  7. Observational
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  9. Article
  10. Article
  11. Article
  12. Article
  13. Determinants of Statin Initiation Among Adult Diabetic Patients in Bonga, Ethiopia.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

A MarcellusiEconomic Evaluation and HTA (EEHTA), CEIS, Faculty of Economics, University of Rome, Tor Vergata, Italy; National Research Council (CNR) - Institute for Research on Population and Social Policies (IRPPS), Rome, Italy.
R VitiEconomic Evaluation and HTA (EEHTA), CEIS , Faculty of Economics, University of Rome , Tor Vergata , Italy.
P SciattellaEconomic Evaluation and HTA (EEHTA), CEIS , Faculty of Economics, University of Rome , Tor Vergata , Italy.
G AimarettiDepartment of Translational Medicine , University of the Eastern Piedmont , Novara, Italy.
S De CosmoComplex Operative Unit of Internal Medicine IRCCS-CSS San Giovanni Rotondo (FG) , Italy.
V ProvenzanoComplex Operative Unit of Diabetology, Partinico Hospital, Partinico (PA) , Italy.
G TonoloDiabetology Center, Local Health Unit 2 Olbia-Tempio , Olbia , Italy.
F S MenniniEconomic Evaluation and HTA (EEHTA), CEIS, Faculty of Economics, University of Rome, Tor Vergata, Italy; Institute for Leadership and Management in Health - KingstonUniversity London, London, UK.
University of Rome Tor Vergata · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITKingston University · GBNational Research Council · ITUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetes mellitus (DM) is a chronic-degenerative disease associated with a high risk of chronic complications and comorbidities. The aim of this study is to estimate the average annual cost incurred by the Italian National Health Service (NHS) for the treatment of DM stratified by patients' comorbidities. Moreover, the model estimates the economic impact of implementing good clinical practice for the management of patients with DM.

methodsData were extrapolated from administrative database of the Marche Region and specific inclusion and exclusion criteria were developed from a clinical board in order to estimate patients with DM only, DM+1, DM+2, DM+3 and DM+4 comorbidities (cardiovascular disease, neuropathy, nephropathy and retinopathy). Regional data were considered a good proxy for implementing a previously developed cost-of-illness (COI) model from Italian NHS perspective already published. A scenario analysis was considered to estimate the economic impact of good clinical practice implementation in the treatment of DM and its comorbidities in Italy.

resultsThe model estimated an average number of patients with DM per year in the Marche region of 85.909 (5.5% of population) from 2008 to 2011. The mean costs per patients with DM only, DM+1, DM+2, DM+3 and DM+4 comorbidities were €341, €1,335, €2,287, €5,231 and €7,085 respectively. From the Italian NHS perspective, the total economic burden of DM in Italy amounted to €8.1. billion/year (22% for drugs, 74% for hospitalization and 4% for visits). Scenario analysis demonstrates that the implementation of good clinical practice could save over €700 million per year.

conclusionsThis model is the first study that considers real world data and COI model to estimate the economic burden of DM and its comorbidities from the Italian NHS perspective. Integrated management of the patients with DM could be a good driver for the reduction of the costs of this disease in Italy.

Indexed as

Cost AnalysisEconomic AnalysisEconomic ImpactInpatient Diabetes Management

Identifiers

PMID27843551
PMCPMC5073526
OpenAlexW2528045837

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.