Evidence map›Paper›PMID 27843538›Full record

ArticleWorld journal of hepatology2016

Reversibility of minimal hepatic encephalopathy following liver transplantation in Egyptian cirrhotic patients.

Mahmoud A Osman, Moataz M Sayed, Khaled A Mansour, Shereen A Saleh, Wesam A Ibrahim, Sara M Abdelhakam, Mohamed Bahaa, Wael A Yousry, Hosam S Elbaz, Reginia N Mikhail and 3 more

Abstract read
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In one paragraph

Article in World journal of hepatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Review
  3. [Guidelines for the diagnosis and management of hepatic encephalopathy in cirrhosis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mahmoud A OsmanMahmoud A Osman, Moataz M Sayed, Khaled A Mansour, Shereen A Saleh, Wesam A Ibrahim, Wael A Yousry, Hosam S Elbaz, Reginia N Mikhail, Department of Internal Medicine, Hepatology and Gastroenterology, Faculty of Medicine, Ain Shams University, Cairo 11341, Egypt.
Moataz M SayedMahmoud A Osman, Moataz M Sayed, Khaled A Mansour, Shereen A Saleh, Wesam A Ibrahim, Wael A Yousry, Hosam S Elbaz, Reginia N Mikhail, Department of Internal Medicine, Hepatology and Gastroenterology, Faculty of Medicine, Ain Shams University, Cairo 11341, Egypt.
Khaled A MansourMahmoud A Osman, Moataz M Sayed, Khaled A Mansour, Shereen A Saleh, Wesam A Ibrahim, Wael A Yousry, Hosam S Elbaz, Reginia N Mikhail, Department of Internal Medicine, Hepatology and Gastroenterology, Faculty of Medicine, Ain Shams University, Cairo 11341, Egypt.
Shereen A SalehMahmoud A Osman, Moataz M Sayed, Khaled A Mansour, Shereen A Saleh, Wesam A Ibrahim, Wael A Yousry, Hosam S Elbaz, Reginia N Mikhail, Department of Internal Medicine, Hepatology and Gastroenterology, Faculty of Medicine, Ain Shams University, Cairo 11341, Egypt.
Wesam A IbrahimMahmoud A Osman, Moataz M Sayed, Khaled A Mansour, Shereen A Saleh, Wesam A Ibrahim, Wael A Yousry, Hosam S Elbaz, Reginia N Mikhail, Department of Internal Medicine, Hepatology and Gastroenterology, Faculty of Medicine, Ain Shams University, Cairo 11341, Egypt.
Sara M AbdelhakamMahmoud A Osman, Moataz M Sayed, Khaled A Mansour, Shereen A Saleh, Wesam A Ibrahim, Wael A Yousry, Hosam S Elbaz, Reginia N Mikhail, Department of Internal Medicine, Hepatology and Gastroenterology, Faculty of Medicine, Ain Shams University, Cairo 11341, Egypt.
Mohamed BahaaMahmoud A Osman, Moataz M Sayed, Khaled A Mansour, Shereen A Saleh, Wesam A Ibrahim, Wael A Yousry, Hosam S Elbaz, Reginia N Mikhail, Department of Internal Medicine, Hepatology and Gastroenterology, Faculty of Medicine, Ain Shams University, Cairo 11341, Egypt.
Wael A YousryMahmoud A Osman, Moataz M Sayed, Khaled A Mansour, Shereen A Saleh, Wesam A Ibrahim, Wael A Yousry, Hosam S Elbaz, Reginia N Mikhail, Department of Internal Medicine, Hepatology and Gastroenterology, Faculty of Medicine, Ain Shams University, Cairo 11341, Egypt.
Hosam S ElbazMahmoud A Osman, Moataz M Sayed, Khaled A Mansour, Shereen A Saleh, Wesam A Ibrahim, Wael A Yousry, Hosam S Elbaz, Reginia N Mikhail, Department of Internal Medicine, Hepatology and Gastroenterology, Faculty of Medicine, Ain Shams University, Cairo 11341, Egypt.
Reginia N MikhailMahmoud A Osman, Moataz M Sayed, Khaled A Mansour, Shereen A Saleh, Wesam A Ibrahim, Wael A Yousry, Hosam S Elbaz, Reginia N Mikhail, Department of Internal Medicine, Hepatology and Gastroenterology, Faculty of Medicine, Ain Shams University, Cairo 11341, Egypt.
Azza M HassanMahmoud A Osman, Moataz M Sayed, Khaled A Mansour, Shereen A Saleh, Wesam A Ibrahim, Wael A Yousry, Hosam S Elbaz, Reginia N Mikhail, Department of Internal Medicine, Hepatology and Gastroenterology, Faculty of Medicine, Ain Shams University, Cairo 11341, Egypt.
Ehab H ElsayedMahmoud A Osman, Moataz M Sayed, Khaled A Mansour, Shereen A Saleh, Wesam A Ibrahim, Wael A Yousry, Hosam S Elbaz, Reginia N Mikhail, Department of Internal Medicine, Hepatology and Gastroenterology, Faculty of Medicine, Ain Shams University, Cairo 11341, Egypt.
Dalia A MahmoudMahmoud A Osman, Moataz M Sayed, Khaled A Mansour, Shereen A Saleh, Wesam A Ibrahim, Wael A Yousry, Hosam S Elbaz, Reginia N Mikhail, Department of Internal Medicine, Hepatology and Gastroenterology, Faculty of Medicine, Ain Shams University, Cairo 11341, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the reversibility of minimal hepatic encephalopathy (MHE) following liver transplantation (LT) in Egyptian cirrhotic patients.

methodsThis prospective study included twenty patients with biopsy-proven liver cirrhosis listed for LT and twenty age- and sex-matched healthy control subjects. All underwent neuro-psychiatric examination, laboratory investigations, radiological studies and psychometric tests including trail making test A (TMT A), TMT B, digit symbol test and serial dotting test. The psychometric hepatic encephalopathy score (PHES) was calculated for patients to diagnose MHE. Psychometric tests were repeated six months following LT in the cirrhotic patient group.

resultsBefore LT, psychometric tests showed highly significant deficits in cirrhotic patients in comparison to controls (

conclusionReversal of MHE in cirrhotic patients could be achieved by LT, especially in those with a MELD score < 15.

Indexed as

CirrhosisLiver transplantationMinimal hepatic encephalopathyModel for end-stage liver disease scorePsychometric tests

Identifiers

PMID27843538
PMCPMC5084057

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.