Evidence map›Paper›PMID 27843198›Full record

ArticleMediators of inflammation2016

Regulation of Autophagy-Related Protein and Cell Differentiation by High Mobility Group Box 1 Protein in Adipocytes.

Huanhuan Feng, Lili Yu, Guojun Zhang, Guoyan Liu, Can Yang, Hui Wang, Xiangfeng Song

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Mediators of inflammation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Role of the DNA repair genesBMJ open diabetes research & care · 2020
    Article
  5. Adiponectin administration alleviates DSS-induced colonic inflammation in Caco-2 cells and mice.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Huanhuan FengSchool of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan Province, China; Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, Xinxiang Medical University, Xinxiang, Henan Province, China.
Lili YuSchool of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan Province, China; Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, Xinxiang Medical University, Xinxiang, Henan Province, China.ORCID 0000-0001-5832-1024
Guojun ZhangSchool of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan Province, China; Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, Xinxiang Medical University, Xinxiang, Henan Province, China.
Guoyan LiuSchool of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan Province, China; Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, Xinxiang Medical University, Xinxiang, Henan Province, China.
Can YangSchool of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan Province, China; Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, Xinxiang Medical University, Xinxiang, Henan Province, China.
Hui WangHenan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, Xinxiang Medical University, Xinxiang, Henan Province, China.ORCID 0000-0002-2454-3814
Xiangfeng SongSchool of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan Province, China; Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, Xinxiang Medical University, Xinxiang, Henan Province, China.ORCID 0000-0002-6498-2678
Xinxiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High mobility group box 1 protein (HMGB1) is a molecule related to the development of inflammation. Autophagy is vital to maintain cellular homeostasis and protect against inflammation of adipocyte injury. Our recent work focused on the relationship of HMGB1 and autophagy in 3T3-L1 cells.

Indexed as

3T3-L1 CellsAdipocytesAdipose TissueAnimalsBlotting, WesternBody WeightCell DifferentiationDiet, High-FatEnzyme-Linked Immunosorbent AssayHMGB1 ProteinMiceMice, Inbred C3HMicrotubule-Associated ProteinsRecombinant ProteinsHMGB1 ProteinMap1lc3b protein, mouseMicrotubule-Associated ProteinsRecombinant Proteins

Identifiers

PMID27843198
PMCPMC5098089
OpenAlexW2536991834

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.