ArticleCarbohydrate polymers2017
Structure-activity relationship of the exopolysaccharide from a psychrophilic bacterium: A strategy for cryoprotection.
Article in Carbohydrate polymers, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed.
- Marine Delivery Vehicles: Molecular Components and Applications of Bacterial Extracellular Vesicles.Marine drugs · 2024Review
- Helping proteins come in from the cold: 5 burning questions about cold-active enzymes.BBA advances · 2024Review
- Chemical modification of bacterial exopolysaccharides: Antioxidant properties and health potentials.Current research in food science · 2024Review
- Exploring Extremophiles from Bulgaria: Biodiversity, Biopolymer Synthesis, Functional Properties, Applications.Polymers · 2023Review
- A laboratory ice machine as a cold oligotrophic artificial microbial niche for biodiscovery.Scientific reports · 2023Article
- Marine versus Non-Marine Bacterial Exopolysaccharides and Their Skincare Applications.Marine drugs · 2023Review
- Probiogenomic Analysis of Lactiplantibacillus sp. LM14-2 from Fermented Mussel (Hoi-dong), and Evaluation of its Cholesterol-lowering and Immunomodulation Effects.Probiotics and antimicrobial proteins · 2023Article
- The Unusual Dominance of the Yeast GenusJournal of fungi (Basel, Switzerland) · 2023Article
- Diverse Repertoire and Relationship of Exopolysaccharide Genes in Cold-AdaptedMicroorganisms · 2023Article
- Comprehensive insights on environmental adaptation strategies in Antarctic bacteria and biotechnological applications of cold adapted molecules.Frontiers in microbiology · 2023Review
- Exopolysaccharides from Marine Microbes: Source, Structure and Application.Marine drugs · 2022Review
- Sugar-Assisted Cryopreservation of Stem Cell-Laden Gellan Gum-Collagen Interpenetrating Network Hydrogels.Biomacromolecules · 2022Article
- Chemical approaches to cryopreservation.Nature reviews. Chemistry · 2022Review
- Membrane and Extracellular Matrix Glycopolymers ofFrontiers in microbiology · 2022Article
- Proteomic andFrontiers in microbiology · 2022Article
- Characterization, immunostimulatory and antitumor activities of a β-galactoglucofurannan from cultivatedFrontiers in nutrition · 2022Article
- Psychrophilic Bacterial Phosphate-Biofertilizers: A Novel Extremophile for Sustainable Crop Production under Cold Environment.Microorganisms · 2021Review
- Industrial applications of cold-adapted enzymes: challenges, innovations and future perspective.3 Biotech · 2021Review
- Identification of Biomolecules Involved in the Adaptation to the Environment of Cold-Loving Microorganisms and Metabolic Pathways for Their Production.Biomolecules · 2021Review
- Cold Active Lipases: Biocatalytic Tools for Greener Technology.Applied biochemistry and biotechnology · 2021Review
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
Microrganisms from sea ice, glacial and subglacial environments are currently under investigation due to their relevant ecological functions in these habitats, and to their potential biotechnological applications. The cold-adapted Colwellia psychrerythraea 34H produces extracellular polysaccharides with cryoprotection activity. We here describe the purification and detailed molecular primary and secondary structure of the exopolysaccharide (EPS) secreted by C. psychrerythraea 34H cells grown at 4°C. The structure was determined by chemical analysis and NMR. The trisaccharide repeating unit of the EPS is constituted by a N-acetyl quinovosamine unit and two residues of galacturonic acid both decorated with alanine. In addition, the EPS was tested in vitro showing a significant inhibitory effect on ice recrystallization. In-depth NMR and computational analysis suggest a pseudohelicoidal structure which seems to prevent the local tetrahedral order of the water molecules in the first hydration shell, and could be responsible of the inhibition of ice recrystallization. As cell cryopreservation is an essential tool in modern biotechnology and medicine, the observations reported in this paper could pave the way for a biotechnological application of Colwellia EPS.
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