Evidence map›Paper›PMID 27842605›Full record

ArticleWorld journal of surgical oncology2016

A case of neuroendocrine carcinoma in the hepatic hilar lymph nodes concomitant with an adenocarcinoma of the gallbladder.

Haruka Okada, Yoichiro Uchida, Naomi Matsuzaki, Toru Goto, Satoshi Nishimura, Akira Kurita, Takafumi Nishimura, Shujiro Yazumi, Hiroaki Terajima

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of surgical oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Haruka OkadaDepartment of Gastroenterological Surgery and Oncology, The Tazuke Kofukai Medical Research Institute, Kitano Hospital, 2-4-20 Ohgimachi, kita-ku, Osaka City, Osaka, 530-8480, Japan.
Yoichiro UchidaDepartment of Gastroenterological Surgery and Oncology, The Tazuke Kofukai Medical Research Institute, Kitano Hospital, 2-4-20 Ohgimachi, kita-ku, Osaka City, Osaka, 530-8480, Japan. uchiday@kuhp.kyoto-u.ac.jp.
Naomi MatsuzakiDepartment of Pathology, The Tazuke Kofukai Medical Research Institute, Kitano Hospital, Osaka, Japan.
Toru GotoDepartment of Gastroenterological Surgery and Oncology, The Tazuke Kofukai Medical Research Institute, Kitano Hospital, 2-4-20 Ohgimachi, kita-ku, Osaka City, Osaka, 530-8480, Japan.
Satoshi NishimuraDepartment of Gastroenterology and Hepatology, The Tazuke Kofukai Medical Research Institute, Kitano Hospital, Osaka, Japan.
Akira KuritaDepartment of Gastroenterology and Hepatology, The Tazuke Kofukai Medical Research Institute, Kitano Hospital, Osaka, Japan.
Takafumi NishimuraDepartment of Medical Oncology, The Tazuke Kofukai Medical Research Institute, Kitano Hospital, Osaka, Japan.
Shujiro YazumiDepartment of Gastroenterology and Hepatology, The Tazuke Kofukai Medical Research Institute, Kitano Hospital, Osaka, Japan.
Hiroaki TerajimaDepartment of Gastroenterological Surgery and Oncology, The Tazuke Kofukai Medical Research Institute, Kitano Hospital, 2-4-20 Ohgimachi, kita-ku, Osaka City, Osaka, 530-8480, Japan.
Kitano Hospital · JPKyoto Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeuroendocrine tumors (NETs) are rare especially in the gallbladder. They have not been elucidated in the pathogenesis, clinicopathological characteristics, and treatment options. CASE PRESENTATION: We present a 76-year-old woman with a gallbladder tumor and hepatic hilar lymph node swelling. The lymph node biopsy demonstrated neuroendocrine carcinoma (NEC). We performed cholecystectomy, hepatic hilar lymphadenectomy, extrahepatic biliary duct resection, and hepaticojejunostomy prior to chemotherapy. Pathological examination revealed the gallbladder mass was an adenocarcinoma invading to the muscular layer without any NEC components, whereas the hepatic hilar lymph nodes were filled with high-grade NEC cells with negligible area of adenocarcinoma. The patient received general chemotherapy consisting of carboplatin and etoposide, but a recurrence in the para-aortic lymph nodes occurred 4 months after surgery.

conclusionsWe report a rare case of NEC of the hepatic hilar lymph nodes that were concomitant with an adenocarcinoma of the gallbladder. High-grade NEC generally has an aggressive behavior and an optimal treatment strategy should be chosen for each patient.

Indexed as

AdenocarcinomaAgedBile Ducts, ExtrahepaticBiomarkers, TumorBiopsyCarcinoma, NeuroendocrineChemotherapy, AdjuvantCholangiopancreatography, Magnetic ResonanceCholecystectomyEndoscopic Ultrasound-Guided Fine Needle AspirationEndoscopy, GastrointestinalFatal OutcomeFemaleFluorodeoxyglucose F18Gallbladder NeoplasmsHumansBiomarkers, TumorFluorodeoxyglucose F18Gallbladder cancerIntestinal metaplasiaNeuroendocrine carcinomaNeuroendocrine tumor

Identifiers

PMID27842605
PMCPMC5109806
OpenAlexW2555071007

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.