Evidence map›Paper›PMID 27842558›Full record

ArticleWorld journal of surgical oncology2016

Perivascular epithelioid cell tumor of the descending colon mimicking a gastrointestinal stromal tumor: a case report.

Ryuta Iwamoto, Tatsuki R Kataoka, Ayako Furuhata, Kazuo Ono, Seiichi Hirota, Kenji Kawada, Yoshiharu Sakai, Hironori Haga

Open access · goldAbstract readCase Reports
In one paragraph

Article in World journal of surgical oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ryuta IwamotoDepartment of Diagnostic Pathology, Kyoto University Hospital, 54 Syogoinkawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Tatsuki R KataokaDepartment of Diagnostic Pathology, Kyoto University Hospital, 54 Syogoinkawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan. trkataoka@yahoo.co.jp.
Ayako FuruhataDepartment of Diagnostic Pathology, Kyoto University Hospital, 54 Syogoinkawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Kazuo OnoDepartment of Pathology, Japan Red Cross Society Wakayama Medical Center, 4-20 Komatsubara-dori, Wakayama, 640-8558, Japan.
Seiichi HirotaDepartment of Surgical Pathology, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan.
Kenji KawadaDepartment of Surgery, Kyoto University Hospital, 54 Syogoinkawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Yoshiharu SakaiDepartment of Surgery, Kyoto University Hospital, 54 Syogoinkawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Hironori HagaDepartment of Diagnostic Pathology, Kyoto University Hospital, 54 Syogoinkawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Kyoto University Hospital · JPKomatsu (Japan) · JPHyogo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe present a case of perivascular epithelioid cell tumor (PEComa), which clinically and histologically mimics a gastrointestinal stromal tumor (GIST). CASE PRESENTATION: A 42-year-old woman was found to have a mass in the left flank during her annual medical checkup. Computed tomography examination revealed a submucosal tumor of the descending colon. Surgeons and radiologists suspected that the lesion was a GIST, and left hemicolectomy was performed without biopsy. Microscopic examination showed that the lesion was composed of spindle and epithelioid cells, which were immunohistochemically negative for c-kit and positive for platelet-derived growth factor receptor (PDGFR) α. Initial diagnosis of PDGFRα-positive GIST was made. However, gene analysis did not reveal mutations in PDGFRα. Additional immunohistochemistry showed that tumor cells were positive for human melanin black 45 (HMB45), melanA, and the myogenic marker calponin. A final diagnosis of PEComa was made.

conclusionPEComa should be included in the differential diagnosis of PDGFRα-positive spindle cell tumors in the wall of the gastrointestinal tract.

Indexed as

AdultBiopsyCalcium-Binding ProteinsCalponinsColectomyColon, DescendingColonic NeoplasmsDiagnosis, DifferentialFemaleGastrointestinal Stromal TumorsHumansImmunohistochemistryMART-1 AntigenMicrofilament ProteinsMutationPerivascular Epithelioid Cell NeoplasmsCalcium-Binding ProteinsCalponinsMART-1 AntigenMicrofilament ProteinsProto-Oncogene Proteins c-kitReceptor, Platelet-Derived Growth Factor alphaGastrointestinal stromal tumorKITPerivascular epithelioid cell tumorPlatelet-derived growth factor receptor

Identifiers

PMID27842558
PMCPMC5109728
OpenAlexW2553699884

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.