Observational studyRespiratory research2016
Rising total costs and mortality rates associated with admissions due to COPD exacerbations.
Observational study in Respiratory research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- The economic burden of chronic obstructive pulmonary disease (COPD) in Europe: results from a systematic review of the literature.The European journal of health economics : HEPAC : health economics in prevention and care · 2020Pooled it
- Characteristics and real-world health clinical outcomes of uncontrolled COPD patients: population-based study in France.ERJ open research · 2025Article
- Economic Burden of Uncontrolled COPD Under Triple Therapy: A Population-Based Study.International journal of chronic obstructive pulmonary disease · 2025Article
- Impact of Increased Use of Single-Inhaler Triple Therapies on COPD Exacerbation Rates, Mortality, and Total Costs: PROMETHEUS France.International journal of chronic obstructive pulmonary disease · 2025Article
- Association Between Mechanical Power and 28-Day All-Cause Mortality in Chronic Obstructive Pulmonary Disease Patients Undergoing Invasive Ventilation: Analysis of the MIMIC-IV Database.International journal of chronic obstructive pulmonary disease · 2025Observational
- Factors associated with undiagnosed COPD in patients hospitalised for severe COPD exacerbation.BMJ open respiratory research · 2024Article
- Predicting outcomes in patients with exacerbation of COPD requiring mechanical ventilation.Annals of intensive care · 2024Article
- Psychosocial Support in Pulmonary Rehabilitation.Respiratory care · 2024Review
- Characteristics, treatments, in-hospital and long-term outcomes among inpatients with acute exacerbation of chronic obstructive pulmonary disease in China: sex differences in a large cohort study.BMC pulmonary medicine · 2024Article
- Insufficient Pulmonary Rehabilitation Uptake After Severe Exacerbation of COPD: A Multicentre Study in the South West Region of France.International journal of chronic obstructive pulmonary disease · 2024Article
- Efficacy and safety of oral corticosteroids to treat outpatients with acute exacerbations of COPD in primary care: a multicentre pragmatic randomised controlled study.ERJ open research · 2023Article
- Pulmonary rehabilitation after severe exacerbation of COPD: a nationwide population study.Respiratory research · 2023Article
- Association between increased mortality and bronchial fibroscopy in intensive care units and intermediate care units during COPD exacerbations: an analysis of the 2014 and 2015 National French Medical-based Information System Databases (PMSI).Journal of intensive care · 2021Article
- Women's COPD.Frontiers in medicine · 2021Review
- Article
- Prevalence of sarcopenia and malnutrition during acute exacerbation of COPD and after 6 months recovery.European journal of clinical nutrition · 2020Article
- Identification of Patient Profiles with High Risk of Hospital Re-Admissions for Acute COPD Exacerbations (AECOPD) in France Using a Machine Learning Model.International journal of chronic obstructive pulmonary disease · 2020Article
- [Influence of co-morbidities on the progression and prognosis of patients with chronic obstructive pulmonary disease in a Tunisian Hospital].The Pan African medical journal · 2020Article
- Effect of OEnvironmental science and pollution research international · 2019Article
- Medicaid Expansion and Mechanical Ventilation in Asthma, Chronic Obstructive Pulmonary Disease, and Heart Failure.Annals of the American Thoracic Society · 2019Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo examine trends in mortality, costs and in-hospital management and outcomes of severe COPD exacerbations admitted in France.
methodsPatients hospitalized from 2007 to 2012 with COPD exacerbation as the primary diagnosis were identified from the exhaustive French medico-administrative hospitalizations database records. Four groups of severe COPD exacerbations were defined: hospitalisation in a general ward (GW) without acute respiratory failure (ARF), GW with ARF, ICU without invasive mechanical ventilation (MV), and ICU with MV.
resultsA 15.48 % increase in admissions from 113 276 in 2007 to 133 497 in 2012 was recorded. Age (+9.9 months), gender (-2.5 % of male) and length of stay (-0.29 day) slightly changed while the number of ICU admissions increased markedly (+41.78 %). In-hospital mortality rates increased (+8.06 %, p < .001) and followed seasonal variations peaking in winter. Total hospitalizations costs increased from 602 to 678 millions euros (+12.6 %). Pneumonia-related mortality increased (+37.2 %). A progressive replacement of chest X-ray by CT scan was observed (-41.3 % vs +31.7 %) while fewer spirometries (-13.7 %) and bronchoscopies (-22.6 %) were performed.
conclusionThe incidence of severe COPD exacerbations and the proportion of ICU-managed patients are still increasing in France. Rising total costs and mortality rates especially related to pneumonia advocate for rethinking COPD management plans.
trial registrationNot applicable.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.