Evidence map›Paper›PMID 27842381›Full record

ArticleNature2016

The pathway to GTPase activation of elongation factor SelB on the ribosome.

Niels Fischer, Piotr Neumann, Lars V Bock, Cristina Maracci, Zhe Wang, Alena Paleskava, Andrey L Konevega, Gunnar F Schröder, Helmut Grubmüller, Ralf Ficner and 2 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Nature, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 121 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Engineered mRNA-ribosome fusions for facile biosynthesis of selenoproteins.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  11. How Dedicated Ribosomes Translate a Leaderless mRNA.Journal of molecular biology · 2024
    Article
  12. Tuning tRNAs for improved translation.Frontiers in genetics · 2024
    Review
  13. Review
  14. Biosynthesis, Engineering, and Delivery of Selenoproteins.International journal of molecular sciences · 2023
    Review
  15. Review
  16. Article
  17. Structural insight into translation initiation of thebioRxiv : the preprint server for biology · 2023
    Article
  18. Modulation of translational decoding by mNature communications · 2023
    Article
  19. Article
  20. Review

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Niels FischerDepartment of Structural Dynamics, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
Piotr NeumannDepartment of Molecular Structural Biology, Institute for Microbiology and Genetics, GZMB, Georg-August University Göttingen, Justus-von Liebig Weg 11, 37077 Göttingen, Germany.
Lars V BockDepartment of Theoretical and Computational Biophysics, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
Cristina MaracciDepartment of Physical Biochemistry, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
Zhe WangInstitute of Complex Systems (ICS-6), Forschungszentrum Jülich, 52425 Jülich, Germany.
Alena PaleskavaDepartment of Physical Biochemistry, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
Andrey L KonevegaDepartment of Physical Biochemistry, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
Gunnar F SchröderInstitute of Complex Systems (ICS-6), Forschungszentrum Jülich, 52425 Jülich, Germany.
Helmut GrubmüllerDepartment of Theoretical and Computational Biophysics, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
Ralf FicnerDepartment of Molecular Structural Biology, Institute for Microbiology and Genetics, GZMB, Georg-August University Göttingen, Justus-von Liebig Weg 11, 37077 Göttingen, Germany.
Marina V RodninaDepartment of Physical Biochemistry, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
Holger StarkDepartment of Structural Dynamics, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
Max Planck Institute for Biophysical Chemistry · DEForschungszentrum Jülich · DEUniversity of Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In all domains of life, selenocysteine (Sec) is delivered to the ribosome by selenocysteine-specific tRNA (tRNA

Indexed as

Bacterial ProteinsBinding SitesCodon, TerminatorCryoelectron MicroscopyEndoribonucleasesEnzyme ActivationEscherichia coliFungal ProteinsGTP PhosphohydrolasesModels, MolecularNucleic Acid ConformationProtein BindingProtein BiosynthesisProtein DomainsRibosomesRibosome Subunits, Large, Bacterialalpha-sarcinBacterial ProteinsCodon, TerminatorEndoribonucleasesFungal ProteinsGTP PhosphohydrolasesRicinRNA, Transfer, Amino Acid-SpecificSelB protein, BacteriaSelenocysteinetRNA, selenocysteine-

Identifiers

PMID27842381
OpenAlexW2550234534

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.