Evidence map›Paper›PMID 27841853›Full record

ArticleNature microbiology2016

Retroviruses integrate into a shared, non-palindromic DNA motif.

Paul D W Kirk, Maxime Huvet, Anat Melamed, Goedele N Maertens, Charles R M Bangham

Abstract read
In one paragraph

Article in Nature microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Tumor Antigens beyond the Human Exome.International journal of molecular sciences · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Latency Reversing Agents: Kick and Kill of HTLV-1?International journal of molecular sciences · 2021
    Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Cellular and molecular mechanisms of HIV-1 integration targeting.Cellular and molecular life sciences : CMLS · 2018
    Review
  16. Article
  17. Human T-cell leukaemia virus type 1: parasitism and pathogenesis.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017
    Review
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Paul D W KirkMRC Biostatistics Unit, Cambridge Institute for Public Health, Cambridge CB2 0SR, UK.
Maxime HuvetDepartment of Life Sciences, Centre for Integrative Systems Biology and Bioinformatics, Imperial College London, London SW7 2AZ, UK.
Anat MelamedSection of Virology, Division of Infectious Diseases, Imperial College London, London SW7 2AZ, UK.
Goedele N MaertensSection of Virology, Division of Infectious Diseases, Imperial College London, London SW7 2AZ, UK.
Charles R M BanghamSection of Virology, Division of Infectious Diseases, Imperial College London, London SW7 2AZ, UK.

Funding

Medical Research Council MC_UP_0801/1Medical Research Council MC_UU_00002/10Wellcome Trust
6 · The paper itself

Abstract

Many DNA-binding factors, such as transcription factors, form oligomeric complexes with structural symmetry that bind to palindromic DNA sequences

Indexed as

Nucleotide MotifsVirus IntegrationAnimalsHumansRetroviridae

Identifiers

PMID27841853
PMCPMC7613964

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.