Evidence map›Paper›PMID 27841836›Full record

ArticleThe Clinical journal of pain2017

Pressure Pain Threshold and Anxiety in Adolescent Females With and Without Juvenile Fibromyalgia: A Pilot Study.

Christopher D King, Kristen E Jastrowski Mano, Kimberly A Barnett, Megan Pfeiffer, Tracy V Ting, Susmita Kashikar-Zuck

Abstract read
In one paragraph

Article in The Clinical journal of pain, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Functional Status and Body Mass Index in Postmenopausal Women with Fibromyalgia: A Case-control Study.International journal of environmental research and public health · 2019
    Article
  14. Review
  15. Article
  16. A narrative review on the difficulties associated with fibromyalgia diagnosis.Therapeutic advances in musculoskeletal disease · 2018
    Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christopher D King*Department of Pediatric Anesthesia ‡Division of Behavioral Medicine and Clinical Psychology §Division of Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center †Department of Psychology, University of Cincinnati ∥University of Cincinnati College of Medicine, Cincinnati, OH.
Kristen E Jastrowski Mano
Kimberly A Barnett
Megan Pfeiffer
Tracy V Ting
Susmita Kashikar-Zuck

Funding

LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., KISSELA, BRETT M · 2015 to 2024
$37.5M
Behavioral Interventions and Long Term Outcomes in Juvenile Fibromyalgia SyndromeK24AR056687 · NIAMS · CINCINNATI CHILDRENS HOSP MED CTR · PI KASHIKAR-ZUCK, SUSMITA · 2009 to 2018
$1.4M
Physiological correlates of endogenous pain mod in healthy individuals with TMJDR00DE022368 · NIDCR · CINCINNATI CHILDRENS HOSP MED CTR · PI KING, CHRISTOPHER D · 2015 to 2017
$718k
NCATS NIH HHS UL1 TR001425NIAMS NIH HHS K24 AR056687NIDCR NIH HHS R00 DE022368
6 · The paper itself

Abstract

objectivesReduced pain thresholds have been documented in adult fibromyalgia, but there are no quantitative studies of altered pain sensitivity in adolescents with juvenile fibromyalgia (JFM). The current study examined differences in pressure pain sensitivity between adolescent females with JFM and healthy controls. The relationship between levels of anxiety and pain were also examined.

methodsA total of 34 JFM (15.4±1.4 y old) and 31 controls (14.5±1.3 y old) completed self-report measures of pain and anxiety. Pressure pain threshold was assessed (palm and forehead sites) with a hand-held algometer. Participants indicated the first sensation of pain and then rated the intensity of pain on a Numerical Rating Scale.

resultsAdolescents with JFM exhibited greater sensitivity to pressure pain compared with controls. While the difference between JFM and controls was only observed at the forehead, the intensity of pain produced by the pressure algometry at both sites was significantly higher in the JFM participants compared with controls. Correlations between clinical pain and anxiety were significant for the JFM group only. No relationships were observed between anxiety and pressure pain for either group. DISCUSSION: This study is a first step toward investigating mechanisms of altered pain processing in adolescents with JFM. Adolescents with JFM were found be more sensitive to pressure pain than their healthy peers, which suggests a propensity for sensitization of peripheral and/or central nociceptive information often reported in adult fibromyalgia, and which does not appear to be affected by anxiety.

Indexed as

AdolescentAnxietyFemaleFibromyalgiaHumansHyperalgesiaPainPain MeasurementPain ThresholdPhysical StimulationPilot ProjectsPressurePsychiatric Status Rating ScalesRetrospective Studies

Identifiers

PMID27841836
PMCPMC6368956

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.