ArticleRadiology2017
PET of Poly (ADP-Ribose) Polymerase Activity in Cancer: Preclinical Assessment and First In-Human Studies.
Erratum issuedOpen access · greenAbstract read
In one paragraph
Article in Radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 50 papers.
0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 75 citations in OpenAlex.
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- Pharmacodynamic Activity of [JCO precision oncology · 2024Article
- [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023Article
- Advances in PET imaging of cancer.Nature reviews. Cancer · 2023Review
- Preclinical evaluation of a brain penetrant PARP PET imaging probe in rat glioblastoma and nonhuman primates.European journal of nuclear medicine and molecular imaging · 2023Article
- Current status of contemporary diagnostic radiotracers in the management of breast cancer: first steps toward theranostic applications.EJNMMI research · 2023Review
- [18F]FluorThanatrace ([18F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023Article
- Polyethylene Glycol 3350 (PEG 3350) as a Practical Vehicle for Rapid Reconstitution of PARPi-FL Formulations for Clinical Use.Molecular imaging and biology · 2023Article
- Pilot Study: PARP1 Imaging in Advanced Prostate Cancer.Molecular imaging and biology · 2022Article
- Pre-clinical investigation of astatine-211-parthanatine for high-risk neuroblastoma.Communications biology · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
15 authors at 4 institutions in 1 country.
Loren S MichelFrom the Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY (L.S.M.); Division of Radiological Sciences, Mallinckrodt Institute of Radiology (S.D., F.J.B., K.J.S., J.T.E., S.P., C.B., W.C., D.Z., R.L., D.L.C.), and Department of Internal Medicine (S.L., B.T., A.W.G.), Washington University School of Medicine, 510 S Kingshighway Blvd, Campus Box 8225, St Louis, MO 63110; and Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (R.H.M.).
Samantha DyroffFrom the Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY (L.S.M.); Division of Radiological Sciences, Mallinckrodt Institute of Radiology (S.D., F.J.B., K.J.S., J.T.E., S.P., C.B., W.C., D.Z., R.L., D.L.C.), and Department of Internal Medicine (S.L., B.T., A.W.G.), Washington University School of Medicine, 510 S Kingshighway Blvd, Campus Box 8225, St Louis, MO 63110; and Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (R.H.M.).
Frank J BrooksFrom the Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY (L.S.M.); Division of Radiological Sciences, Mallinckrodt Institute of Radiology (S.D., F.J.B., K.J.S., J.T.E., S.P., C.B., W.C., D.Z., R.L., D.L.C.), and Department of Internal Medicine (S.L., B.T., A.W.G.), Washington University School of Medicine, 510 S Kingshighway Blvd, Campus Box 8225, St Louis, MO 63110; and Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (R.H.M.).
Katherine J SpaydFrom the Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY (L.S.M.); Division of Radiological Sciences, Mallinckrodt Institute of Radiology (S.D., F.J.B., K.J.S., J.T.E., S.P., C.B., W.C., D.Z., R.L., D.L.C.), and Department of Internal Medicine (S.L., B.T., A.W.G.), Washington University School of Medicine, 510 S Kingshighway Blvd, Campus Box 8225, St Louis, MO 63110; and Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (R.H.M.).
Sora LimFrom the Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY (L.S.M.); Division of Radiological Sciences, Mallinckrodt Institute of Radiology (S.D., F.J.B., K.J.S., J.T.E., S.P., C.B., W.C., D.Z., R.L., D.L.C.), and Department of Internal Medicine (S.L., B.T., A.W.G.), Washington University School of Medicine, 510 S Kingshighway Blvd, Campus Box 8225, St Louis, MO 63110; and Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (R.H.M.).
Jacquelyn T EngleFrom the Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY (L.S.M.); Division of Radiological Sciences, Mallinckrodt Institute of Radiology (S.D., F.J.B., K.J.S., J.T.E., S.P., C.B., W.C., D.Z., R.L., D.L.C.), and Department of Internal Medicine (S.L., B.T., A.W.G.), Washington University School of Medicine, 510 S Kingshighway Blvd, Campus Box 8225, St Louis, MO 63110; and Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (R.H.M.).
Sharon PhillipsFrom the Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY (L.S.M.); Division of Radiological Sciences, Mallinckrodt Institute of Radiology (S.D., F.J.B., K.J.S., J.T.E., S.P., C.B., W.C., D.Z., R.L., D.L.C.), and Department of Internal Medicine (S.L., B.T., A.W.G.), Washington University School of Medicine, 510 S Kingshighway Blvd, Campus Box 8225, St Louis, MO 63110; and Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (R.H.M.).
Benjamin TanFrom the Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY (L.S.M.); Division of Radiological Sciences, Mallinckrodt Institute of Radiology (S.D., F.J.B., K.J.S., J.T.E., S.P., C.B., W.C., D.Z., R.L., D.L.C.), and Department of Internal Medicine (S.L., B.T., A.W.G.), Washington University School of Medicine, 510 S Kingshighway Blvd, Campus Box 8225, St Louis, MO 63110; and Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (R.H.M.).
Andrea Wang-GillamFrom the Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY (L.S.M.); Division of Radiological Sciences, Mallinckrodt Institute of Radiology (S.D., F.J.B., K.J.S., J.T.E., S.P., C.B., W.C., D.Z., R.L., D.L.C.), and Department of Internal Medicine (S.L., B.T., A.W.G.), Washington University School of Medicine, 510 S Kingshighway Blvd, Campus Box 8225, St Louis, MO 63110; and Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (R.H.M.).
Christopher BognarFrom the Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY (L.S.M.); Division of Radiological Sciences, Mallinckrodt Institute of Radiology (S.D., F.J.B., K.J.S., J.T.E., S.P., C.B., W.C., D.Z., R.L., D.L.C.), and Department of Internal Medicine (S.L., B.T., A.W.G.), Washington University School of Medicine, 510 S Kingshighway Blvd, Campus Box 8225, St Louis, MO 63110; and Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (R.H.M.).
Wenhua ChuFrom the Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY (L.S.M.); Division of Radiological Sciences, Mallinckrodt Institute of Radiology (S.D., F.J.B., K.J.S., J.T.E., S.P., C.B., W.C., D.Z., R.L., D.L.C.), and Department of Internal Medicine (S.L., B.T., A.W.G.), Washington University School of Medicine, 510 S Kingshighway Blvd, Campus Box 8225, St Louis, MO 63110; and Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (R.H.M.).
Dong ZhouFrom the Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY (L.S.M.); Division of Radiological Sciences, Mallinckrodt Institute of Radiology (S.D., F.J.B., K.J.S., J.T.E., S.P., C.B., W.C., D.Z., R.L., D.L.C.), and Department of Internal Medicine (S.L., B.T., A.W.G.), Washington University School of Medicine, 510 S Kingshighway Blvd, Campus Box 8225, St Louis, MO 63110; and Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (R.H.M.).
Robert H MachFrom the Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY (L.S.M.); Division of Radiological Sciences, Mallinckrodt Institute of Radiology (S.D., F.J.B., K.J.S., J.T.E., S.P., C.B., W.C., D.Z., R.L., D.L.C.), and Department of Internal Medicine (S.L., B.T., A.W.G.), Washington University School of Medicine, 510 S Kingshighway Blvd, Campus Box 8225, St Louis, MO 63110; and Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (R.H.M.).
Richard LaforestFrom the Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY (L.S.M.); Division of Radiological Sciences, Mallinckrodt Institute of Radiology (S.D., F.J.B., K.J.S., J.T.E., S.P., C.B., W.C., D.Z., R.L., D.L.C.), and Department of Internal Medicine (S.L., B.T., A.W.G.), Washington University School of Medicine, 510 S Kingshighway Blvd, Campus Box 8225, St Louis, MO 63110; and Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (R.H.M.).
Delphine L ChenFrom the Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY (L.S.M.); Division of Radiological Sciences, Mallinckrodt Institute of Radiology (S.D., F.J.B., K.J.S., J.T.E., S.P., C.B., W.C., D.Z., R.L., D.L.C.), and Department of Internal Medicine (S.L., B.T., A.W.G.), Washington University School of Medicine, 510 S Kingshighway Blvd, Campus Box 8225, St Louis, MO 63110; and Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (R.H.M.).
Mallinckrodt (United States) · USWashington University in St. Louis · USMemorial Sloan Kettering Cancer Center · USUniversity of Pennsylvania · US
Funding
Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0MPOSITRON EMISSION TOMOGRAPHIC IMAGING OF LUNG TRANSPLANTR01HL121218 · NHLBI · WASHINGTON UNIVERSITY · PI CHEN, DELPHINE L, GELMAN, ANDREW ERIC · 2014 to 2017
$2.8MNCI NIH HHS P30 CA091842NHLBI NIH HHS R01 HL121218
Abstract
Purpose To demonstrate that positron emission tomography (PET) with fluorine 18 (
Indexed as
AdultAnimalsBenzamidesBiomarkers, PharmacologicalBiomarkers, TumorCase-Control StudiesFemaleFluorine RadioisotopesHumansLiver NeoplasmsMaleMiceMice, NudeMiddle AgedPancreatic NeoplasmsPhthalazinesBenzamidesBiomarkers, PharmacologicalBiomarkers, TumorFluorine RadioisotopesiniparibolaparibPhthalazinesPiperazinesPoly(ADP-ribose) Polymerase InhibitorsPoly(ADP-ribose) Polymerases
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.