Evidence map›Paper›PMID 27841718›Full record

ArticleCell cycle (Georgetown, Tex.)2017

Low-dose methotrexate enhances cycling of highly anaplastic cancer cells.

Maria Grazia Cipolleschi, Ilaria Marzi, Elisabetta Rovida, Massimo Olivotto, Persio Dello Sbarba

Open access · bronzeAbstract read
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. The new anticancer era: Tumor metabolism targeting.Cell cycle (Georgetown, Tex.) · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Maria Grazia Cipolleschia Department of Experimental and Clinical Biomedical Sciences "Mario Serio ," Università degli Studi di Firenze , Florence , Italy.
Ilaria Marzia Department of Experimental and Clinical Biomedical Sciences "Mario Serio ," Università degli Studi di Firenze , Florence , Italy.
Elisabetta Rovidaa Department of Experimental and Clinical Biomedical Sciences "Mario Serio ," Università degli Studi di Firenze , Florence , Italy.
Massimo Olivottoa Department of Experimental and Clinical Biomedical Sciences "Mario Serio ," Università degli Studi di Firenze , Florence , Italy.
Persio Dello Sbarbaa Department of Experimental and Clinical Biomedical Sciences "Mario Serio ," Università degli Studi di Firenze , Florence , Italy.
University of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We previously showed that cellular RedOx state governs the G

Indexed as

Amino AcidsAnimalsCell CycleCell Line, TumorDose-Response Relationship, DrugFolic AcidMaleMetabolic Networks and PathwaysMethotrexateNeoplasmsRats, WistarAmino AcidsFolic AcidMethotrexatecancer stem cellscell cyclefolatesglycinemethotrexateserine

Identifiers

PMID27841718
PMCPMC5323031
OpenAlexW2551701809

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.